Mucopolysaccharidosis Type 4A

Condition 101

What is the definition of Mucopolysaccharidosis Type 4A?

Mucopolysaccharidosis type IVA (MPS IVA, also called Morquio syndrome, type A) is a metabolic condition that primarily affects the skeleton. The severity, age of onset, and associated symptoms vary significantly from person to person and range from a severe and rapidly progressive, early-onset form ...

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What are the alternative names for Mucopolysaccharidosis Type 4A?

  • MPS 4A
  • Morquio A disease
  • Galactosamine-6-sulfatase deficiency
  • GALNS deficiency
  • Morquio disease type A
  • MPS4A
  • Mucopolysaccharidosis type 4A
  • N-acetylgalactosamine-6-sulfate sulfatase deficiency
  • Morquio syndrome A

Latest Research

Latest Advance
  • Condition: Atlantoaxial Instability in Morquio Syndrome
  • Journal: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
  • Treatment Used: Free-Hand C1-C2 Fusion
  • Number of Patients: 1
  • Published —
The study researched the use of free-hand C1-C2 fusion for patients with atlantoaxial instability in Morquio syndrome.

Clinical Trials

Clinical Trial
  • Status: Recruiting
  • Study Type: Drug
  • Participants: 30
  • Start Date: November 7, 2018
A Randomized Clinical Trial to Evaluate the Effects of Losartan on Cardiovascular Disease in Patients With Mucopolysaccharidoses IV A and VI
Clinical Trial
  • Status: Recruiting
  • Study Type: Other
  • Participants: 12
  • Start Date: May 10, 2017
Pregnancy With Morquio Syndrome - What Are Patients' Perspectives and Has ERT Changed Them?
Clinical Trial
  • Status: Recruiting
  • Study Type: Biological
  • Participants: 1500
  • Start Date: January 11, 2012
Longitudinal Study of Neurodegenerative Disorders