Mucormycosis is a fungal infection of the sinuses, brain, or lungs. It occurs in some people with a weakened immune system.
Fungal infection - mucormycosis; Zygomycosis
Mucormycosis is caused by different kinds of fungi that are often found in decaying organic matter. These include spoiled bread, fruit, and vegetables, as well as soil and compost piles. Most people come in contact with the fungus at some time.
However, people with a weakened immune system are more likely to develop mucormycosis. These include people with any of the following conditions:
Mucormycosis may involve:
Symptoms of rhinocerebral mucormycosis include:
Symptoms of lung (pulmonary) mucormycosis include:
Symptoms of gastrointestinal mucormycosis include:
Symptoms of kidney (renal) mucormycosis include:
Symptoms of skin (cutaneous) mucormycosis include a single, sometimes painful, hardened area of skin that may have a blackened center.
Surgery should be done right away to remove all dead and infected tissue. Surgery can lead to disfiguration because it may involve removal of the palate, parts of the nose, or parts of the eye. But, without such aggressive surgery, chances of survival are greatly decreased.
You will also receive antifungal medicine, usually amphotericin B, through a vein. After the infection is under control, you may be switched to a different medicine such as posaconazole or isavuconazole.
If you have diabetes, it will be important to get your blood sugar in the normal range.
Oliver Cornely is in Cologne, Germany. Cornely is rated as an Elite expert by MediFind in the treatment of Mucormycosis. He is also highly rated in 29 other conditions, according to our data. His top areas of expertise are Mucormycosis, Aspergillosis, Agranulocytosis, and Allergic Bronchopulmonary Aspergillosis.
Philipp Koehler is in Koeln, Germany. Koehler is rated as an Elite expert by MediFind in the treatment of Mucormycosis. He is also highly rated in 10 other conditions, according to our data. His top areas of expertise are Mucormycosis, Aspergillosis, Sepsis, and Allergic Bronchopulmonary Aspergillosis.
Danila Seidel is in Koeln, Germany. Seidel is rated as an Elite expert by MediFind in the treatment of Mucormycosis. They are also highly rated in 2 other conditions, according to our data. Their top areas of expertise are Mucormycosis, Aspergillosis, HIV/AIDS, and Agranulocytosis.
Mucormycosis has a very high death rate, even when aggressive surgery is done. Risk of death depends on the area of the body involved and your overall health.
These complications may occur:
People with weakened immune systems and immune disorders (including diabetes) should seek medical attention if they develop:
Because the fungi that cause mucormycosis are widespread, the best way to prevent this infection is to improve control of the illnesses associated with mucormycosis.
Published Date : December 24, 2020
Published By : Jatin M. Vyas, MD, PhD, Assistant Professor in Medicine, Harvard Medical School; Assistant in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, MA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
Centers for Disease Control and Prevention website. Mucormycosis. www.cdc.gov/fungal/diseases/mucormycosis/index.html. Updated October 28, 2020. Accessed February 18, 2021.
Kontoyiannis DP. Mucormycosis. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 320.
Kontoyiannis DP, Lewis RE. Agents of mucormycosis and entomophthoramycosis. In: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 9th ed. Philadelphia, PA: Elsevier; 2020:chap 258.