Learn About Multiple Mononeuropathy

What is the definition of Multiple Mononeuropathy?

Multiple mononeuropathy is a nervous system disorder that involves damage to at least two separate nerve areas. Neuropathy means a disorder of the nerves.

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What are the alternative names for Multiple Mononeuropathy?

Mononeuritis multiplex; Mononeuropathy multiplex; Multifocal neuropathy; Peripheral neuropathy - mononeuritis multiplex

What are the causes of Multiple Mononeuropathy?

Multiple mononeuropathy is a form of damage to one or more peripheral nerves. These are the nerves outside the brain and spinal cord. It is a group of symptoms (syndrome), not a disease.

However, certain diseases can cause the injury or nerve damage that leads to the symptoms of multiple mononeuropathy. Common conditions include:

  • Blood vessel diseases such as polyarteritis nodosa
  • Connective tissue diseases such as rheumatoid arthritis or systemic lupus erythematosus (the most common cause in children)
  • Diabetes

Less common causes include:

  • Amyloidosis, an abnormal buildup of proteins in tissues and organs
  • Blood disorders (such as hypereosinophilia and cryoglobulinemia)
  • Infections such as Lyme disease, HIV/AIDS, or hepatitis
  • Leprosy
  • Sarcoidosis, inflammation of the lymph nodes, lungs, liver, eyes, skin, or other tissues
  • Sjögren syndrome, a disorder in which the glands that produce tears and saliva are destroyed
  • Granulomatosis with polyangiitis, an inflammation of the blood vessel
What are the symptoms of Multiple Mononeuropathy?

Symptoms depend on the specific nerves involved, and may include:

  • Loss of bladder or bowel control
  • Loss of sensation in one or more areas of the body
  • Paralysis in one or more areas of the body
  • Tingling, burning, pain, or other abnormal sensations in one or more areas of the body
  • Weakness in one or more areas of the body
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What are the current treatments for Multiple Mononeuropathy?

The goals of treatment are to:

  • Treat the illness that is causing the problem, if possible
  • Provide supportive care to maintain independence
  • Control symptoms

To improve independence, treatments may include:

  • Occupational therapy
  • Orthopedic help (for example, a wheelchair, braces, and splints)
  • Physical therapy (for example, exercises and retraining to increase muscle strength)
  • Vocational therapy

Safety is an important for people with sensation or movement problems. Lack of muscle control and decreased sensation may increase the risk for falls or injuries. Safety measures include:

  • Having adequate lighting (such as leaving lights on at night)
  • Installing railings
  • Removing obstacles (such as loose rugs that may slip on the floor)
  • Testing water temperature before bathing
  • Wearing protective shoes (no open toes or high heels)

Check shoes often for grit or rough spots that may injure the feet.

People with decreased sensation should check their feet (or other affected area) often for bruises, open skin areas, or other injuries that may go unnoticed. These injuries may become severely infected because the pain nerves of the area are not signaling the injury.

People with multiple mononeuropathy are prone to new nerve injuries at pressure points such as the knees and elbows. They should avoid putting pressure on these areas, for example, by not leaning on the elbows, crossing the knees, or holding similar positions for long periods.

Medicines that may help include:

  • Over-the-counter or prescription pain drugs
  • Antiseizure or antidepressant drugs to reduce stabbing pains
Who are the top Multiple Mononeuropathy Local Doctors?
Elite
Highly rated in
23
conditions

Università Cattolica Del Sacro Cuore

Rome, IT 

Marco Luigetti is in Rome, Italy. Luigetti is rated as an Elite expert by MediFind in the treatment of Multiple Mononeuropathy. He is also highly rated in 23 other conditions, according to our data. His top areas of expertise are Multiple Mononeuropathy, Accessory Deep Peroneal Nerve, Transthyretin Amyloidosis, and Charcot-Marie-Tooth Disease.

Elite
Highly rated in
7
conditions

Laboratoire D'électroneuromyographie

Electroneuromyography Laboratory, 146 
Paris, FR 75011

Paul Seror is in Paris, France. Seror is rated as an Elite expert by MediFind in the treatment of Multiple Mononeuropathy. He is also highly rated in 7 other conditions, according to our data. His top areas of expertise are Multiple Mononeuropathy, Hereditary Neuralgic Amyotrophy, Mononeuritis Multiplex, and Brachial Plexopathy.

 
 
 
 
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Elite
Highly rated in
12
conditions

Yamaguchi University Graduate School Of Medicine

Yamaguchi, JP 

Michiaki Koga is in Yamaguchi, Japan. Koga is rated as an Elite expert by MediFind in the treatment of Multiple Mononeuropathy. They are also highly rated in 12 other conditions, according to our data. Their top areas of expertise are Multiple Mononeuropathy, Miller-Fisher Syndrome, Guillain-Barre Syndrome, and Rasmussen Encephalitis.

What is the outlook (prognosis) for Multiple Mononeuropathy?

A full recovery is possible if the cause is found and treated, and if the nerve damage is limited. Some people have no disability. Others have a partial or complete loss of movement, function, or sensation.

What are the possible complications of Multiple Mononeuropathy?

Complications may include:

  • Deformity, loss of tissue or muscle mass
  • Disturbances of organ functions
  • Medicine side effects
  • Repeated or unnoticed injury to the affected area due to lack of sensation
  • Relationship problems due to erectile dysfunction
When should I contact a medical professional for Multiple Mononeuropathy?

Call your provider if you notice signs of multiple mononeuropathy.

How do I prevent Multiple Mononeuropathy?

Preventive measures depend on the specific disorder. For example, with diabetes, eating healthy foods and keeping a tight control of blood sugar may help prevent multiple mononeuropathy from developing.

Central nervous system and peripheral nervous system
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What are the Latest Advances for Multiple Mononeuropathy?
Assessment of neuropathic pain in leprosy patients with relapse or treatment failure by infrared thermography: A cross-sectional study.
Aseptic hypertrophic pachymeningitis in a patient with Rheumatoid Arthritis - a case of involvement of the central nervous system by the disease?
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Immunoglobulin G4-related disease presenting with peripheral neuropathy: a case report.
Who are the sources who wrote this article ?

Published Date : June 23, 2020
Published By : Amit M. Shelat, DO, FACP, FAAN, Attending Neurologist and Assistant Professor of Clinical Neurology, Renaissance School of Medicine at Stony Brook University, Stony Brook, NY. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

What are the references for this article ?

Katirji B. Disorders of peripheral nerves. In: Daroff RB, Jankovic J, Mazziotta JC, Pomeroy SL, eds. Bradley's Neurology in Clinical Practice. 7th ed. Philadelphia, PA: Elsevier; 2016:chap 107.

Smith G, Shy ME. Peripheral neuropathies. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 392.