Spectral Analyses of Resting Postural Tremor Measured by Accelerometer and Gyroscope as a Predictive Tool of Multiple Sclerosis
Status: Recruiting
Intervention Type: Behavioral
Study Type: Observational
SUMMARY
Early diagnosis is a key factor for effective treatment of multiple sclerosis. Accelerometer and gyroscope measurement of tremor could screen potential motor control dysfunction and predict a risk for development of multiple sclerosis.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 20
Maximum Age: 70
Healthy Volunteers: t
View:
⁃ Group 1:
• Definite diagnosis of MS
• prevailed motor deficit of upper extremities, but without visible tremor
• stable clinical status in the preceding 3 months
• Expanded Disability Status Scale score (EDSS) ≥ 2 ≤ 7.5, and
• no corticosteroid therapy in the preceding month
⁃ Group 2:
• Healthy volunteers in the age of 20-70 years will be employed
• There will be defined as persons without any neurological disease diagnose at the time of the measurement.
Contact Information
Primary
Kamila Řasová, Ph.D.
kamila.rasova@gmail.com
+420604511416
Time Frame
Start Date: 2021-05-01
Estimated Completion Date: 2024-12-30
Participants
Target number of participants: 30
Treatments
Patients with multiple sclerosis
MS patients will be chosen by an independent neurologist.
Healthy volunteers
Healthy controls will be paired by age and sex with MS patients.
Related Therapeutic Areas
Sponsors
Leads: Charles University, Czech Republic