3D OPTIMIZED WMN MPRAGE Increased Detection of Focal Spinal Cord Lesion in Multiple Sclerosis (WHINUME)
Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The aim of this study is to compare the 3D OPTIMIZED MPRAGE WMN sequence to conventional sequences used in spinal cord analysis. The patients will be explored at the cervical level with the conventional 2D sagittal T2 FSE, 2D sagittal STIR, 2D sagittal PSIR, 3D T1 MPRAGE sequences, and the sequence of interest 3D sagittal OPTIMIZED WMN MPRAGE and 3D axial OPTIMIZED WMN MPRAGE. At the thoracic level, with the conventional 2D sagittal T2 FSE, 2D sagittal STIR, 3D T1 MPRAGE sequences and the sequence of interest 3D sagittal OPTIMIZED WMN MPRAGE.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Patients older than 18 years old
• CIS or RRMS
• Medullary symptomatology less than 6 months
• With or without an objective lesion on a subsequent MRI scan
• Signed the Informed Consent
Locations
Other Locations
France
CHU de Bordeaux
RECRUITING
Bordeaux
Contact Information
Primary
Vincent Dousset, MD, PhD
vincent.dousset@chu-bordeaux.fr
+335 56 79 56 04
Backup
Amaury Ravache, MD
amaury.ravache@chu-bordeaux.fr
Time Frame
Start Date: 2023-08-02
Estimated Completion Date: 2026-05-01
Participants
Target number of participants: 60
Treatments
Experimental: 3D OPTIMIZED WMN MPRAGE
* At the cervical level the conventional data set: 2D Sagittal T2 FSE/ 2D Sagittal STIR / 2D Sagittal PSIR / 3D MPRAGE and the 3D OPTIMIZED MPRAGE WMN data set with sagittal and axial acquisition.~* At the thoracic level the conventional data set: 2D Sagittal T2 FSE/ 2D Sagittal STIR / 3D MPRAGE and the 3D Sagittal OPTIMIZED MPRAGE WMN data set.
Related Therapeutic Areas
Sponsors
Leads: University Hospital, Bordeaux