Effects of Whole-body Electrical Muscle Stimulation Exercise on Spinal Motoneuronal Activation in Older Adults

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

During this pilot study, the investigators will examine the effects of whole-body electrical muscle stimulation exercise (WB-EMS Exercise) on motoneuronal activation in healthy adults, which typically decreases with age. The investigators will also test whether WB-EMS Exercise will improve measures of physical function. Participants will undergo clinical and electrophysiologic testing before and after the WB-EMS Exercise intervention. The WB-EMS Exercise intervention will be delivered two times per week for four weeks. The hypothesis is that whole-body electrical muscle stimulation combined with physical exercise (WB-EMS Exercise) could bypass the problem of insufficient motoneuronal activation to improve exercise effect in older adults.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: t
View:

• Age (65 years or older) for healthy older adults and between 18-39 for healthy younger adults

• Ambulatory without an assistive device

• More than anti-gravity strength in major muscle groups as assessed by manual muscle testing

• Medical clearance to participate in an exercise program

• Ability to conform to the requirements of the study (i.e. attendance at assessment and intervention visits, maintain current level of non-study physical activity for the duration of the study, no intention to relocate mid-study)

Locations
United States
Missouri
NextGen Precision Health Building, Clinical and Translational Science Unit
RECRUITING
Columbia
Contact Information
Primary
Kristina Kelly, DPT, MS
kristina.kelly@health.missouri.edu
5738842596
Backup
W. David Arnold, MD
Time Frame
Start Date: 2025-06-01
Estimated Completion Date: 2025-12
Participants
Target number of participants: 12
Treatments
Experimental: Healthy Adults
All participants will receive the WB-EMS Exercise intervention 2 times per week for 4 weeks. Participants will only perform leveled exercise programs in the Strength Training Mode. These programs are 20-minute videos led by exercise professionals. They are full-body workouts with no one muscle group receiving more attention than another. They consist of 10-12 exercises performed for 14 repetitions. Each repetition takes 4 seconds to complete (the time that the stimulation is on) and is followed by a 4 second rest (the time that the stimulation is off). All exercises occur in a double-limb stance position. Most exercises occur with feet in wide base of support, hips width or more apart. All exercises are modifiable by the healthcare professional administering and monitoring the intervention based on participant's safe and available range of motion (i.e. arm movements, torso positions, extent of knee bend).
Related Therapeutic Areas
Sponsors
Leads: University of Missouri-Columbia

This content was sourced from clinicaltrials.gov

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