Preventing Loss of Autonomy in Older Patients by Improving Diagnosis of Sarcopenia and Monitoring With High-definition Surface Electromyography Technology

Status: Recruiting
Location: See all (6) locations...
Intervention Type: Device, Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Sarcopenia is a progressive and generalised skeletal muscle disorder involving the accelerated loss of muscle mass and function that is associated with increased adverse outcomes including falls, functional decline, frailty, and mortality. In this project, the high-definition surface electromyography technology (HD-sEMG) signals will be analysed to extract features/ markers for the diagnosis of sarcopenia. This is a multicentric, descriptive, cross-sectional, parallel group study to develop a new diagnostic method. It is planned to include 846 people aged 75 years and over hospitalized in the acute geriatric or rehabilitation wards and suspected of sarcopenia (Score ≥4 on the SARC-F screening questionnaire). The inclusion duration will be 18 months and adding a 3-month patient follow-up. The total study duration will be 21 months. Patients will have their body composition using bioimpedancemetry and if possible by dual X-ray absorptiometry (DEXA). Muscular strength will be assessed by handgrip strength. Physical performance will be assessed. Additional data will be collected from their medical records.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 75
Healthy Volunteers: f
View:

• Patient aged 75 years and over

• Score ≥4 on the SARC-F screening questionnaire

• Enrolled in a social security plan (no AME)

• Informed and consenting patient

Locations
Other Locations
France
Hôpital Corentin Celton, APHP
RECRUITING
Issy-les-moulineaux
Hôpital Charles Foix, APHP
RECRUITING
Ivry-sur-seine
Unité d'Explorations fonctionnelles du sujet âgé - Hôpital Charles Foix
NOT_YET_RECRUITING
Ivry-sur-seine
Hôpital Rothschild, APHP
RECRUITING
Paris
Hôpital Rothschild, APHP
RECRUITING
Paris
Hôpital Tenon, APHP
RECRUITING
Paris
Contact Information
Primary
Kiyoka KINUGAWA, Prof. MD PhD
kiyoka.kinugawa@aphp.fr
+331 49 59 47 53
Backup
Sofiane BOUDAOUD, Prof. PhD
sofiane.boudaoud@utc.fr
+(33) 03 44 23 79 29
Time Frame
Start Date: 2025-07-09
Estimated Completion Date: 2027-03
Participants
Target number of participants: 846
Treatments
Experimental: Elderly patients suspected of sarcopenia
Related Therapeutic Areas
Sponsors
Collaborators: Compiègne University of Technology, Centre National de la Recherche Scientifique, France
Leads: Assistance Publique - Hôpitaux de Paris

This content was sourced from clinicaltrials.gov

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