Explore the Effects of Nutritional Supplementation of Leucine and Polyunsaturated Fatty Acids on Muscle Health in the Elderly
Status: Recruiting
Location: See location...
Intervention Type: Dietary supplement
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
Population aging has become a significant global concern, and Taiwan is set to officially enter the super-aged society in 2025. As individuals age, various physiological functions gradually decline, including a reduction in muscle mass, which is a key aspect of the aging process. This interventional study aims to investigate the effects of leucine-rich protein combined with polyunsaturated fatty acid supplementation on middle-aged and elderly individuals (aged 50 and above) who are at high risk for sarcopenia.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 50
Maximum Age: 99
Healthy Volunteers: f
View:
• Age ≥ 50 years
• ASMI \< 7 kg/m2 in men
• ASMI \< 5.7 kg/m2 in women
• Grip strength \< 28 kg in men
• Grip strength \< 18 kg in women
• Walk speed \< 1 m/s
Locations
Other Locations
Taiwan
Chang Gung Memorial Hospital
RECRUITING
Linkou District
Contact Information
Primary
Hsiang-Yu Tang, Ph.D.
tangshyu@cgu.edu.tw
+886-3-2118800
Backup
Yi Tsang Chen, Master of Science
ytchen@fpg.com.tw
+886-2-2712-2211
Time Frame
Start Date: 2025-07-01
Estimated Completion Date: 2026-04-17
Participants
Target number of participants: 90
Treatments
Experimental: Animal-Based Oil Group
Participants in this group will supplement with animal-based poly-unsaturated oil. The supplementation will be maintained for 12 weeks.
Experimental: Plant-Based Oil Group
Participants in this group will supplement with plant-based poly-unsaturated oil. The supplementation will be maintained for 12 weeks.
Related Therapeutic Areas
Sponsors
Leads: Chang Gung Memorial Hospital
Collaborators: Chang Gung University