The Effects of Sarcopenia on Neuromuscular Block in Gastrointestinal Cancer Surgery
This prospective observational study aims to evaluate the effects of sarcopenia on intraoperative neuromuscular block (NMB) in patients undergoing gastrointestinal cancer surgery. Adult patients scheduled for elective gastrointestinal cancer surgery will be grouped as sarcopenic or non-sarcopenic based on preoperative abdominal CT scans. Neuromuscular block parameters, including onset time, depth, duration, and recovery, will be objectively measured using TOF (Train-of-Four) monitoring. The study seeks to determine whether sarcopenia influences sensitivity to muscle relaxants and to contribute to individualized anesthesia management and patient safety.
• Patients aged between 18 and 75 years
• Patients diagnosed with gastrointestinal system (GIS) cancer and scheduled for elective surgery
• Patients who have undergone preoperative abdominal computed tomography (CT) imaging
• Patients classified as American Society of Anesthesiologists (ASA) physical status I-III