Precision Diagnosis and Prospective Cohort Study for Myasthenia Gravis: Multicenter Analysis in China
Status: Recruiting
Location: See all (4) locations...
Intervention Type: Other
Study Type: Observational
SUMMARY
The present study is a prospective cohort study aiming to improve the clinical capacity in the diagnosis and natural history of Chinese patients with myasthenia gravis (MG). 300 MG patients are planned to recruit, document and prospectively follow up. Management of screening test and cohort manifestation are studied.
Eligibility
Participation Requirements
Sex: All
Maximum Age: 90
Healthy Volunteers: f
View:
• fluctuating muscle weakness and fatigability, along with one of the below:
• more than 10% amplitude decrement in low frequency repetitive nerve stimulation,less than 10% amplitude increment in high frequency repetitive nerve stimulation;
• anti-AChR or MuSK antibody positivity;
• positive to the neostigmine test;
• understanding and assigning the informed consent form, and having a good compliance with the follow up.
Locations
Other Locations
China
Children's Hospital of Fudan University
RECRUITING
Shanghai
Huashan Hospital
RECRUITING
Shanghai
Obsterics and Gynecology Hospital of Fudan University
RECRUITING
Shanghai
Shanghai Chest Hospital
RECRUITING
Shanghai
Contact Information
Primary
Chongbo Zhao, MD
zhao_chongbo@fudan.edu.cn
86-021-52889999
Time Frame
Start Date: 2024-02-01
Estimated Completion Date: 2028-05-01
Participants
Target number of participants: 500
Treatments
myasthenia gravis
300 MG patients are anticipated for precision diagnosis and disease monitoring.
Related Therapeutic Areas
Sponsors
Leads: Huashan Hospital