Myelodysplastic Syndrome (MDS) Clinical Trials

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A Pilot Study of Home Blood Transfusions for Patient With Cancer Who Have Transfusion Dependent Cytopenias

Status: Recruiting
Location: See location...
Intervention Type: Procedure
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This is a pilot single arm study to evaluate the feasibility and acceptability of a home blood transfusion program. Patients will be enrolled with hematologic malignancies and other bone marrow failure syndromes who are transfusion dependent and interested in a home blood transfusion program. Participants enrolled in the study will receive 1-5 units of blood products at home. Data on barriers to administration will be recorded. Surveys and qualitative interviews will be completed to better understand acceptability of the program.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
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• Individuals must meet all of the following inclusion criteria in order to be eligible to participate in the study:

• Provide signed and dated informed consent form Willing to comply with all study procedures and be available for the duration of the study

• Male or female, over the age of 18

• Must meet definition of transfusion dependence (require at least 2 blood product transfusions over a 28-day period)

• Receive their cancer care at SKCCC

• Have a history of blood product transfusions and NO history of transfusion reactions,

• Live within a 30-mile range of the Center City SKCCC location.

• Must be willing to allow people into the home

Locations
United States
Pennsylvania
Thomas Jefferson University Hospital
RECRUITING
Philadelphia
Contact Information
Primary
Adam Binder, MD
Adam.Binder@jefferson.edu
215-955-8874
Time Frame
Start Date: 2025-06-03
Estimated Completion Date: 2027-06
Participants
Target number of participants: 30
Treatments
Experimental: Experimental - Home Blood Transfusion
Participants will receive 1-2 blood products transfused in the home each week for a total of 5 transfusions. Participants with known RBC antibodies will only be eligible to receive platelet transfusions at home. Research nurse comes to home early to draw CBC and Type and Screen. Infusion nurse delivers blood products to home. Blood product administered. Assess vital signs following administration of blood products. Perform feasibility, acceptability, appropriateness questionnaires. Complete qualitative semi-structured interviews.
Sponsors
Collaborators: American Cancer Society, Inc.
Leads: Thomas Jefferson University

This content was sourced from clinicaltrials.gov