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Construction of Abnormal Projection Regions of Cognitive Neural Networks in Patients With Anemia Using Functional Near-Infrared Spectroscopy (fNIRS)

Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY

Anemia is a global public health concern and is closely linked to dysfunction of brain cognitive neural networks, a key mechanism underlying cognitive impairment. Such deficits-including declines in memory, learning, processing speed, and executive function-reduce daily living abilities and increase risks of falls and depression. Functional near-infrared spectroscopy (fNIRS) enables real-time monitoring of oxygenated and deoxygenated hemoglobin fluctuations, reflecting brain network function. This study aims to identify affected neural network regions in anemic patients and visualize connectivity changes using heatmaps and arc-based mapping. The findings will support early detection of cognitive impairment and guide precise clinical interventions, ultimately informing individualized treatment strategies to enhance therapeutic outcomes and quality of life.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 65
Healthy Volunteers: f
View:

• Diagnosis of anemia

• First hospitalization

• Male or female, aged 18-65 years

• Willing and able to comply with the requirements for this study and written informed consent

Locations
Other Locations
China
Regenerative Medicine Center
RECRUITING
Tianjin
Contact Information
Primary
ZheXiang Kuang, MSN
kuangzhexiang@ihcams.ac.cn
13920361752
Backup
Xiao Yu, Undergraduate
yuxiao@ihcams.ac.cn
18722218448
Time Frame
Start Date: 2025-10-11
Estimated Completion Date: 2028-12-31
Participants
Target number of participants: 323
Sponsors
Leads: Institute of Hematology & Blood Diseases Hospital, China
Collaborators: Tianjin University

This content was sourced from clinicaltrials.gov

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