Myoclonic Epilepsy Overview

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Learn About Myoclonic Epilepsy

What is the definition of Myoclonic Epilepsy?
Myoclonic epilepsy is a type of seizure disorder characterized by quick jerking movements due to uncontrolled muscle contractions caused by abnormal electrical impulses in the brain. Unlike grand mal (tonic-clonic) seizures, during a myoclonic seizure the affected individual does not lose consciousness. There are several types of myoclonic epilepsy, including infantile spasms, Lennox-Gastaut Syndrome, juvenile myoclonic epilepsy, and progressive myoclonic epilepsy, among others.
What are the symptoms of Myoclonic Epilepsy?
Symptoms of myoclonic epilepsy depend on the type and usually affects the neck, shoulders, and upper arms. Symptoms of myoclonic epilepsy may include quick, uncontrolled muscle jerks; rhythmic movements; arms flinging outward; knees pulling up; body stiffening; and unusual clumsiness. Myoclonic seizures may occur with atonic seizures, which cause limp muscles. When myoclonic epilepsy worsens, it is known as progressive myoclonic epilepsy, which is a rare seizure disorder characterized by both myoclonic and tonic-clonic (grand mal) seizures.
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What are the current treatments for Myoclonic Epilepsy?
Treatment for myoclonic epilepsy depends on the type, frequency, and severity of the seizures and may include anti-seizure (anti-epileptic) medications, ketogenic diet, vagus nerve stimulator (VNS) implantation, and surgery.
Who are the top Myoclonic Epilepsy Local Doctors?
Elite in Myoclonic Epilepsy
Dr. Orrin Devinsky
Neurology | General Surgery
Elite in Myoclonic Epilepsy
Dr. Orrin Devinsky
Neurology | General Surgery

New York University

223 E 34th St, 
New York, NY 
646-558-0800
Languages Spoken:
English
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Orrin Devinsky is a Neurologist and a General Surgeon in New York, New York. Dr. Devinsky is rated as an Elite provider by MediFind in the treatment of Myoclonic Epilepsy. His top areas of expertise are Myoclonic Epilepsy, Dravet Syndrome, Seizures, Epilepsy, and Deep Brain Stimulation.

Elite in Myoclonic Epilepsy
Ingrid E. Scheffer
Elite in Myoclonic Epilepsy
Ingrid E. Scheffer
50 Flemington Rd, 
Parkville, VIC, AU 

Ingrid Scheffer practices in Parkville, Australia. Ms. Scheffer is rated as an Elite expert by MediFind in the treatment of Myoclonic Epilepsy. Her top areas of expertise are Myoclonic Epilepsy, West Syndrome, Epilepsy, and Epilepsy with Myoclonic-Atonic Seizures.

 
 
 
 
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Elite in Myoclonic Epilepsy
Samuel F. Berkovic
Elite in Myoclonic Epilepsy
Samuel F. Berkovic
245 Burgundy St, 
Heidelberg, VIC, AU 

Samuel Berkovic practices in Heidelberg, Australia. Mr. Berkovic is rated as an Elite expert by MediFind in the treatment of Myoclonic Epilepsy. His top areas of expertise are Myoclonic Epilepsy, Epilepsy, Partial Familial Epilepsy, and Epilepsy with Myoclonic-Atonic Seizures.

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What are the latest Myoclonic Epilepsy Clinical Trials?
EMPEROR: A Multicenter, Randomized, Double-blind, Sham-controlled, Parallel Group, Phase 3 Study Evaluating the Efficacy, Safety, and Tolerability of Zorevunersen (STK-001) in Patients With Dravet Syndrome
EMPEROR: A Multicenter, Randomized, Double-blind, Sham-controlled, Parallel Group, Phase 3 Study Evaluating the Efficacy, Safety, and Tolerability of Zorevunersen (STK-001) in Patients With Dravet Syndrome
Enrollment Status: Recruiting
Publish Date: October 08, 2025
Intervention Type: Drug, Other
Study Phase: Phase 3

Summary: The purpose of the study is to evaluate the efficacy, safety, and tolerability of zorevunersen in Patients with Dravet syndrome.

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Observational, Prospective, Multicenter Study of Epidyolex® (Cannabidiol CBD 100 mg/ml) Oral Solution, as Adjunctive Treatment for Seizures Associated With Lennox- Gastaut Syndrome (LGS), Dravet Syndrome (DS) and Tuberous Sclerosis Complex (TSC)
Observational, Prospective, Multicenter Study of Epidyolex® (Cannabidiol CBD 100 mg/ml) Oral Solution, as Adjunctive Treatment for Seizures Associated With Lennox- Gastaut Syndrome (LGS), Dravet Syndrome (DS) and Tuberous Sclerosis Complex (TSC)
Enrollment Status: Recruiting
Publish Date: September 25, 2025
Intervention Type: Drug

Summary: This is a prospective, observational study on approximately 70-100 Real World participants affected by LGS, DS, or TSC treated with Epidyolex® as prescribed in the summary of product characteristics. The eligible participants are expected to participate in the study for a duration of 52 weeks of treatment.

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