Learn About Myositis
Myositis is an inflammation or swelling of the muscles. It is most often caused by injury, infection, medicines, or an autoimmune disorder.
Dermatomyositis and polymyositis are related topics.
Inflammatory myopathies
Johns Hopkins Bayview Medical Center
Andrew Mammen is a Neuromusculoskeletal Medicine specialist and a Neurologist in Baltimore, Maryland. Dr. Mammen is rated as an Elite provider by MediFind in the treatment of Myositis. His top areas of expertise are Myositis, Polymyositis, Dermatomyositis, and Necrotizing Myopathy (NM).
Johns Hopkins Bayview Medical Center
Dr. Christopher-Stine is the Co-Founder and Director of the Johns Hopkins Myositis Center. She is a Professor of Medicine and Neurology. She is a longstanding core faculty member of the Johns Hopkins University School of Medicine College Advisory Program and serves as the Co-Chair of the Johns Hopkins Institutional Review Board (IRB 5). Dr. Christopher-Stine graduated Cum Laude with a B.A. in chemistry from Franklin and Marshall College; was elected to Alpha Omega Alpha at Hahnemann University School of Medicine, where she received her MD degree, and she attained her Masters of Public Health degree from the Johns Hopkins Bloomberg School of Public Health. Her internship and residency training were completed at MCP Hahnemann University, where she also served as Chief Resident. She pursued her rheumatology fellowship training at Johns Hopkins. Dr. Christopher is rated as an Elite provider by MediFind in the treatment of Myositis. Her top areas of expertise are Myositis, Polymyositis, Dermatomyositis, and Inclusion Body Myositis.
Johns Hopkins Bayview Medical Center
Dr. Julie Paik completed her medical school training at the George Washington University School of Medicine in Washington, DC. She then completed her residency and chief residency at UCLA-Cedars-Sinai/VA Medical Center in Los Angeles, California. She completed rheumatology fellowship at Johns Hopkins and joined the faculty in 2013. She currently sees patients at the Johns Hopkins Myositis Center and Scleroderma Center. Her research interests are in myositis and scleroderma or overlap myositis. She also has a special interest in novel therapeutics in refractory dermatomyositis. This provider is registered with the Florida Department of Health to perform telehealth services for patients in Florida. Dr. Paik is rated as an Elite provider by MediFind in the treatment of Myositis. Her top areas of expertise are Dermatomyositis, Polymyositis, Myositis, and Scleroderma.
Background: * Like other complex diseases, autoimmune diseases are the result of numerous causes, including genetic and environmental factors. Some researchers believe that people who are susceptible to autoimmune disorders develop them when the body reacts to environmental or other factors by creating white blood cells that attack the body s own tissues, which then progresses to autoimmune diseases. These im...
Summary: This is a single-arm, open-label, multicenter, ascending dose Phase 1 study evaluating the safety and preliminary efficacy of CTX112 in adult subjects with refractory autoimmune diseases, including active systemic lupus erythematosus (SLE), systemic sclerosis (SSc), or idiopathic inflammatory myopathy (IIM).
Published Date: April 01, 2025
Published By: Linda J. Vorvick, MD, Clinical Professor Emeritus, Department of Family Medicine, UW Medicine, School of Medicine, University of Washington, Seattle, WA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.
Doughty CT, Amato AA. Disorders of the skeletal muscle. In: Jankovic J, Mazziotta JC, Pomeroy SL, Newman NJ, eds. Bradley and Daroff's Neurology in Clinical Practice. 8th ed. Philadelphia, PA: Elsevier Inc; 2022:chap 109.
Selcen D. Muscle diseases. In: Goldman L, Cooney KA, eds. Goldman- Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 389.
Taber's Cyclopedic Medical Dictionary. 24th ed. Philadelphia, PA: F.A. Davis Company; 2021. Myositis. www.tabers.com/tabersonline/view/Tabers-Dictionary/729759/all/myositis. Accessed March 31, 2025.