Myositis
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Learn About Myositis

What is the definition of Myositis?

Myositis is an inflammation or swelling of the muscles. It is most often caused by injury, infection, medicines, or an autoimmune disorder.

Dermatomyositis and polymyositis are related topics.

What are the alternative names for Myositis?

Inflammatory myopathies

Who are the top Myositis Local Doctors?
Chester V. Oddis
Elite in Myositis
Elite in Myositis

UPMC Arthritis And Autoimmunity Center

3601 5th Avenue, Suite 2B, 
Pittsburgh, PA 
Recognized by The Myositis Association
Languages Spoken:
English
Accepting New Patients
Offers Telehealth

Chester V. Oddis, MD is a noted researcher in the clinical, epidemiological and serologic description of the idiopathic inflammatory myopathies. He has completed epidemiological studies on the incidence of polymyositis and dermatomyositis as well as longitudinal studies on functional disability in myositis patients. His focus has been in the autoantibody patterns in patients with inflammatory myopathy and their peculiar immunogenetic associations.Dr. Oddis has written extensively on the diagnosis and management of patients with myositis. He has published and lectured on the use of novel immunosuppressive agents such as tacrolimus (formerly FK506) in the treatment of patients with refractory myositis. This represents the only reported experience of this particular drug in the pharmacologic treatment of inflammatory myopathy. In collaboration with the Department of Neurology, he has assessed the efficacy and utility of outpatient needle muscle biopsy in the diagnosis of inflammatory myopathy. This is important given the cost-containment focus of the current health-care market.Dr. Oddis is the co-investigator on an important national NIH funded study on the efficacy of doxycycline in preventing the progression of knee osteoarthritis in middle-aged women. This study is the first of its kind in assessing the effect of a disease-modifying agent in osteoarthritis.Board certified in internal medicine and rheumatology, Dr. Oddis received his medical degree from Pennsylvania State University, Milton S. Hershey Medical Center and his undergraduate degree from the University of Pittsburgh. He completed his residency in internal medicine at Penn State and fellowship at the University of Pittsburgh Medical Center. Dr. Oddis is rated as an Elite provider by MediFind in the treatment of Myositis. His top areas of expertise are Dermatomyositis, Myositis, Polymyositis, and Antisynthetase Syndrome.

Andrew L. Mammen
Elite in Myositis
Neuromusculoskeletal Medicine | Neurology
Elite in Myositis
Neuromusculoskeletal Medicine | Neurology

Johns Hopkins Bayview Medical Center

4940 Eastern Avenue, Bayview Medical Offices, Level 01 (G), Clinic 5, Bayview Medical Offices, Level 01 (G), Clinic 5, 
Baltimore, MD 
Recognized by The Myositis Association
Languages Spoken:
English

Andrew Mammen is a Neuromusculoskeletal Medicine specialist and a Neurologist in Baltimore, Maryland. Dr. Mammen is rated as an Elite provider by MediFind in the treatment of Myositis. His top areas of expertise are Myositis, Dermatomyositis, Polymyositis, and Necrotizing Myopathy (NM).

 
 
 
 
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Lisa Christopher
Elite in Myositis
Elite in Myositis

Johns Hopkins Bayview Medical Center

4940 Eastern Avenue, Bayview Medical Offices, Level 01 (G), Clinic 5, Bayview Medical Offices, Level 01 (G), Clinic 5, 
Baltimore, MD 
Recognized by The Myositis Association
Languages Spoken:
English
Offers Telehealth

Dr. Christopher-Stine is the Co-Founder and Director of the Johns Hopkins Myositis Center. She is a Professor of Medicine and Neurology. She is a longstanding core faculty member of the Johns Hopkins University School of Medicine College Advisory Program and serves as the Co-Chair of the Johns Hopkins Institutional Review Board (IRB 5). Dr. Christopher-Stine graduated Cum Laude with a B.A. in chemistry from Franklin and Marshall College; was elected to Alpha Omega Alpha at Hahnemann University School of Medicine, where she received her MD degree, and she attained her Masters of Public Health degree from the Johns Hopkins Bloomberg School of Public Health. Her internship and residency training were completed at MCP Hahnemann University, where she also served as Chief Resident. She pursued her rheumatology fellowship training at Johns Hopkins. Dr. Christopher is rated as an Elite provider by MediFind in the treatment of Myositis. Her top areas of expertise are Myositis, Polymyositis, Dermatomyositis, and Inclusion Body Myositis.

What are the latest Myositis Clinical Trials?
An Open-label, Phase I Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD5492 Following Single-ascending Dose and Step-up Dose Administration to Adult Participants With Systemic Lupus Erythematosus or Idiopathic Inflammatory Myopathies or Rheumatoid Arthritis

Summary: The purpose of this study is to measure the safety, tolerability, PK, and PD of AZD5492 administered subcutaneously in adult participants with SLE or IIM or RA Study details include: • The study duration will be a minimum of 180 days in addition to the screening period. Additional follow-up visits may be required up to 12 months from study start. * Depending on the study part they are assigned to,...

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A Phase Ib Study of Nivolumab in Patients With Autoimmune Disorders and Advanced Malignancies (AIM-NIVO)

Summary: This phase Ib trial studies the side effects of nivolumab and to see how well it works in treating patients with autoimmune disorders and cancer that has spread to other places in the body or cannot removed by surgery. Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and sprea...

Who are the sources who wrote this article ?

Published Date: April 01, 2025
Published By: Linda J. Vorvick, MD, Clinical Professor Emeritus, Department of Family Medicine, UW Medicine, School of Medicine, University of Washington, Seattle, WA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

What are the references for this article ?

Doughty CT, Amato AA. Disorders of the skeletal muscle. In: Jankovic J, Mazziotta JC, Pomeroy SL, Newman NJ, eds. Bradley and Daroff's Neurology in Clinical Practice. 8th ed. Philadelphia, PA: Elsevier Inc; 2022:chap 109.

Selcen D. Muscle diseases. In: Goldman L, Cooney KA, eds. Goldman- Cecil Medicine. 27th ed. Philadelphia, PA: Elsevier; 2024:chap 389.

Taber's Cyclopedic Medical Dictionary. 24th ed. Philadelphia, PA: F.A. Davis Company; 2021. Myositis. www.tabers.com/tabersonline/view/Tabers-Dictionary/729759/all/myositis. Accessed March 31, 2025.