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The Effect of Inspiratory Muscle Training on the Functional Status of Patients With Inflammatory Myopathy

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Inflammatory myopathies are rare autoimmune diseases leading to progressive muscle weakness, often including the respiratory muscles. This study aims to investigate whether inspiratory muscle training (IMT) using a threshold device can improve functional status in patients with inflammatory myopathy. Thirty-three patients will undergo a 3-month home-based IMT program with progressive resistance. Functional capacity, inspiratory muscle strength, lung function, diaphragmatic mobility, fatigue, and quality of life will be assessed at baseline and during follow-up. The primary hypothesis is that IMT will enhance inspiratory muscle strength and translate into better functional performance and quality of life.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Diagnosis of inflammatory myopathy according to European Alliance of Associations for Rheumatology / American College of Rheumatology criteria

• Age ≥ 18 years

• Stable clinical condition allowing participation in physical activity

• Ability to understand and follow instructions

• Written informed consent to participate in the study

Locations
Other Locations
Poland
University Clinical Center of the Medical University of Warsaw
RECRUITING
Warsaw
Contact Information
Primary
Jan Sznajder, PhD
jan.sznajder@awf.edu.pl
+48696994812
Backup
Agnieszka Lewińska, PhD
agnieszka.lewinska@awf.edu.pl
+48790013404
Time Frame
Start Date: 2024-08-12
Estimated Completion Date: 2026-12
Participants
Target number of participants: 33
Treatments
Experimental: Inspiratory Muscle Training (IMT)
Patients with inflammatory myopathy will perform a 3-month inspiratory muscle training (IMT) program using a threshold device (Philips Respironics Threshold IMT). Training will be home-based, preceded by individual instruction, and monitored through exercise diaries and follow-up phone consultations. Assessments will be performed before training, after 3 months, and during follow-up visits.
Related Therapeutic Areas
Sponsors
Leads: Józef Piłsudski University of Physical Education

This content was sourced from clinicaltrials.gov