Latest Advances

  • Condition: Brain Metastasis from Soft Tissue Sarcomas
  • Journal: Anticancer research
  • Treatment Used: Combined Surgery and Radiotherapy
  • Number of Patients: 509
  • Published —
This study tested the safety and efficacy of using a combined surgery and radiotherapy regimen to treat patients with brain metastases that they acquired from their soft tissue sarcoma.
  • Condition: High-Risk Soft Tissue Sarcomas
  • Journal: Journal of clinical oncology : official journal of the American Society of Clinical Oncology
  • Treatment Used: Add-on Chemotherapy
  • Number of Patients: 287
  • Published —
The study researched the outcomes of chemotherapy in treating high-risk soft tissue sarcomas.
  • Condition: Patient with De-Differentiated Liposarcoma (DDLPS)
  • Journal: Medicine
  • Treatment Used: Trabectedin
  • Number of Patients: 1
  • Published —
This case report discusses a 68-year-old man diagnosed with advanced metastatic de-differentiated liposarcoma (DDLPS) treated with long-term trabectedin.
  • Condition: Metastatic and/or Un-Resectable Sarcomas
  • Journal: European journal of cancer (Oxford, England : 1990)
  • Treatment Used: Lurbinectedin as Single Agent or in Combination with Conventional Chemotherapy
  • Number of Patients: 42
  • Published —
This study determined the disease control rate at 24 weeks of lurbinectedin alone or with chemotherapy in soft tissue sarcoma (STS).
  • Condition: Retroperitoneal soft tissue sarcoma
  • Journal: European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
  • Treatment Used: Intraoperative radiation therapy and high cumulative radiation doses
  • Number of Patients: 272
  • Published —
The study researched the outcomes of intraoperative radiation therapy and high cumulative radiation doses for patients with retroperitoneal soft tissue sarcoma.
  • Condition: Patients with Unresectable and Relapsed Soft-Tissue Sarcoma (STS) in Japan
  • Journal: Cancer
  • Treatment Used: Trabectedin
  • Number of Patients: 140
  • Published —
This study investigated the effectiveness and safety through postmarketing surveillance of trabectedin in patients with unresectable and relapsed soft-tissue sarcomas (STSs).
  • Condition: Myxoid Liposarcoma in Extremities
  • Journal: Orthopaedic surgery
  • Treatment Used: Wide Resection
  • Number of Patients: 34
  • Published —
This study evaluated treatments and prognostic factors for the myxoid liposarcoma in extremities.
  • Condition: Advanced Leiomyosarcoma/Liposarcoma
  • Journal: Cancer
  • Treatment Used: Trabectedin
  • Number of Patients: 378
  • Published —
This study aimed to report the safety and effectiveness of trabectedin in patients with advanced leiomyosarcoma/liposarcoma.
  • Condition: Soft Tissue Sarcoma
  • Journal: Japanese journal of clinical oncology
  • Treatment Used: Eribulin
  • Number of Patients: 256
  • Published —
This study tested the safety and efficacy of using eribulin to treat patients with soft tissue sarcoma.
  • Condition: Locally Advanced Soft-Tissue Sarcoma
  • Journal: The Lancet. Oncology
  • Treatment Used: NBTXR3, a First-in-Class Radioenhancer Hafnium Oxide (HfO2) Nanoparticle, plus Radiotherapy vs. Radiotherapy Alone
  • Number of Patients: 180
  • Published —
This study evaluated the safety and effectiveness of the hafnium oxide (HfO2) nanoparticle NBTXR3 activated by radiotherapy versus radiotherapy alone as a pre-operative treatment in patients with locally advanced soft-tissue sarcoma.
  • Condition: Advanced Liposarcoma or Leiomyosarcoma
  • Journal: Cancer
  • Treatment Used: Trabectedin Versus Dacarbazine
  • Number of Patients: 577
  • Published —
In this study, researchers compared the effectiveness of trabectedin versus dacarbazine for the treatment of advanced liposarcoma or leiomyosarcoma.
  • Condition: EWSR1/FUS-NFATc2 Rearranged Round Cell Sarcoma
  • Journal: Human pathology
  • Treatment Used: Neoadjuvant Chemotherapy and Surgical Excision
  • Number of Patients: 4
  • Published —
This study evaluated the outcome in patients with small round cell tumor of the bone that harbor NFATc2 rearrangements.
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