Hepatic Histopathology in Urea Cycle Disorders
Status: Recruiting
Location: See all (2) locations...
Study Type: Observational
SUMMARY
This is a multi-site, retrospective chart review as well as a prospective study to evaluate histopathologic findings in liver samples from individuals with any UCD diagnosis. This study will be conducted at all Urea Cycle Disorders Consortium (UCDC) sites: Baylor College of Medicine in Houston, TX and Children's National Medical Center in Washington D.C.
Eligibility
Participation Requirements
Sex: All
Healthy Volunteers: f
View:
• Diagnosis of primary urea cycle disorder based on clinical suspicion confirmed by enzyme activity, DNA testing or metabolite analysis.
• History of liver transplantation and/or liver biopsy OR
• Planned liver transplantation and/or liver biopsy
Locations
United States
Washington, D.c.
Children's National Medical Center
NOT_YET_RECRUITING
Washington D.c.
Texas
Baylor College of Medicine
RECRUITING
Houston
Contact Information
Primary
Saima Ali, MSN
saima.ali@bcm.edu
832-822-4183
Time Frame
Start Date: 2022-02-24
Estimated Completion Date: 2026-06-30
Participants
Target number of participants: 70
Related Therapeutic Areas
Sponsors
Collaborators: Children's National Research Institute
Leads: Baylor College of Medicine