Learn About Necrosis

What is the definition of Necrosis?

Necrosis is the death of body tissue. It occurs when too little blood flows to the tissue. This can be from injury, radiation, or chemicals. Necrosis cannot be reversed.

When large areas of tissue die due to a lack of blood supply, the condition is called gangrene.

Meningococcemia on the calves
Meningococcemia on the leg
Meningococcemia associated purpura
Necrosis of the toes
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Who are the top Necrosis Local Doctors?
SR
Surinder S. Rana
Elite
Highly rated in
41
conditions

Postgraduate Institute Of Medical Education And Research

Post Graduate Institute Of Medical Education And Research, 160 012, 
Chandigarh, CH, IN 

Surinder Rana practices in Chandigarh, India. Rana is rated as an Elite expert by MediFind in the treatment of Necrosis. They are also highly rated in 41 other conditions, according to our data. Their top areas of expertise are Hereditary Pancreatitis, Necrosis, Acute Pancreatitis, Endoscopy, and Stent Placement.

AL
Andreas Linkermann
Elite
Highly rated in
3
conditions

University Hospital Carl Gustav Carus At The Technische Universität Dresden

Biotechnology Center, 
Dresden, SN, DE 

Andreas Linkermann practices in Dresden, Germany. Linkermann is rated as an Elite expert by MediFind in the treatment of Necrosis. He is also highly rated in 3 other conditions, according to our data. His top areas of expertise are Necrosis, Acute Tubular Necrosis, Hypertension, Kidney Transplant, and Heart Transplant.

 
 
 
 
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LG
Loic P. Guillevin
Elite
Highly rated in
29
conditions

Cochin Hospital, Université Paris-Descartes

Paris, FR 

Loic Guillevin practices in Paris, France. Guillevin is rated as an Elite expert by MediFind in the treatment of Necrosis. He is also highly rated in 29 other conditions, according to our data. His top areas of expertise are Necrotizing Vasculitis, Vasculitis, Granulomatosis with Polyangiitis, Eosinophilic Granulomatosis with Polyangiitis (EGPA, Churg-Strauss Syndrome), and Kidney Transplant.

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What are the latest Necrosis Clinical Trials?
A Phase 3B, Multicenter, Randomized, Double-blind, Placebo-controlled Study Evaluating the Efficacy and Safety of Guselkumab Administered Subcutaneously in Participants With Active Psoriatic Arthritis Who Had an Inadequate Response and/or Intolerance to One Prior Anti-Tumor Necrosis Factor Alpha Agent
Who is this study for: Patients with active psoriatic arthritis and inadequate response and/or intolerance to a prior anti-tumor necrosis factor
Enrollment Status: Recruiting
Publish Date: February 15, 2023
Intervention Type: Drug
Study Drug: Guselkumab
Study Phase: Phase 3

Summary: The purpose of this study is to evaluate the efficacy of guselkumab treatment in participants with active psoriatic arthritis (PsA) and inadequate response (IR) and/or intolerance to a prior anti-tumor necrosis factor (TNF) by assessing the reduction in signs and symptoms of PsA.

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THUNDER: Acute Ischemic Stroke Study With the Penumbra System® Including Thunderbolt™ Aspiration Tubing
Enrollment Status: Recruiting
Publish Date: February 15, 2023
Intervention Type: Device
Study Phase: Not Applicable

Summary: The objective of this study is to demonstrate the safety and efficacy of the Penumbra System including Thunderbolt Aspiration Tubing (Thunderbolt) in a population presenting with acute ischemic stroke (AIS) secondary to intracranial large vessel occlusion (LVO) who are eligible for mechanical thrombectomy.

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What are the Latest Advances for Necrosis?
The impact of embolization on radiosurgery obliteration rates for brain arteriovenous malformations: a systematic review and meta-analysis.
Condition: Intracranial Arteriovenous Malformations (AVW)
Journal: Neurosurgical review
Treatment Used: Pre-Stereotactic Radiosurgery (SRS) Embolization
Number of Patients: 7103
Published: December 28, 2022
Primary Squamous Cell Carcinoma of the Liver with Good Response to Carboplatin and 5-Flurouracil: A Case Report.
Condition: Primary Squamous Cell Carcinoma (SCC) of the Liver
Journal: Medicina (Kaunas, Lithuania)
Treatment Used: Carboplatin and 5-Flurouracil (5-FU)
Number of Patients: 1
Published: December 23, 2022
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Ductus arteriosus banding to regulate excessive pulmonary blood flow in a neonate with necrotizing enterocolitis and complex congenital heart disease, including pulmonary atresia and total anomalous pulmonary venous return: a case report.
Condition: Neonate with Necrotizing Enterocolitis (NEC) and Complex Congenital Heart Disease
Journal: Journal of cardiothoracic surgery
Treatment Used: Ductus Arteriosus (DA) Banding
Number of Patients: 1
Published: December 20, 2022
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Who are the sources who wrote this article ?

Published Date: July 30, 2021
Published By: Anna C. Edens Hurst, MD, MS, Associate Professor in Medical Genetics, The University of Alabama at Birmingham, Birmingham, AL. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

What are the references for this article ?

Oakes SA. Cell injury, cell death, and adaptations. In: Kumar V, Abbas AK, Aster JC, eds. Robbins & Cotran Pathologic Basis of Disease. 10th ed. Philadelphia, PA: Elsevier;2021:chap 2.