Learn About Necrosis

What is the definition of Necrosis?

Necrosis is the death of body tissue. It occurs when too little blood flows to the tissue. This can be from injury, radiation, or chemicals. Necrosis cannot be reversed.

When large areas of tissue die due to a lack of blood supply, the condition is called gangrene.

Who are the top Necrosis Local Doctors?
Leuven, VLG, BE 

Severine Vermeire practices in Leuven, Belgium. Vermeire and is rated as an Elite expert by MediFind in the treatment of Necrosis. Her top areas of expertise are Hemorrhagic Proctocolitis, Ulcerative Colitis, Colitis, Endoscopy, and Colonoscopy.

Copenhagen, DK 

Bente Glintborg practices in Copenhagen, Denmark. Glintborg and is rated as an Elite expert by MediFind in the treatment of Necrosis. Her top areas of expertise are Arthritis, Necrosis, Psoriatic Arthritis, and Rheumatoid Arthritis (RA).

 
 
 
 
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399 Bathurst Street, 
Toronto, ON, CA 

Dafna Gladman practices in Toronto, Canada. Gladman and is rated as an Elite expert by MediFind in the treatment of Necrosis. Her top areas of expertise are Psoriatic Arthritis, Psoriasis, Arthritis, Systemic Lupus Erythematosus (SLE), and Kidney Transplant.

What are the latest Necrosis Clinical Trials?
Interleukin-1 Blockade in Acute Myocardial Infarction to Prevent Heart Failure: The Virginia - Anakinra Remodeling Trial 4

Summary: Patients who have a heart attack are at high risk for future development of heart failure ('weakening of the heart'). The researchers believe that the reaction of the heart muscle to injury (inflammation) during a heart attack may be contributing to the risk of heart failure. The current study will test the ability of an anti-inflammatory medicine (anakinra) to block the inflammation in the body d...

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The Role of Inflammation in Cognitive Dysfunction in Acute Depression as Determined by Experimental Inhibition of Tumor Necrosis Factor-alpha Signaling in a Randomized Controlled Trial.

Summary: This study is a mechanistic randomized controlled trial that investigates whether inhibition of tumor necrosis factor signaling via intravenous infusion of infliximab improves psychomotor speed and executive functioning in depressed individuals who exhibit an inflammatory phenotype.

Who are the sources who wrote this article ?

Published Date: September 18, 2023
Published By: Anna C. Edens Hurst, MD, MS, Associate Professor in Medical Genetics, The University of Alabama at Birmingham, Birmingham, AL. Review provided by VeriMed Healthcare Network. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team.

What are the references for this article ?

Oakes SA. Cell injury, cell death, and adaptations. In: Kumar V, Abbas AK, Aster JC, eds. Robbins & Cotran Pathologic Basis of Disease. 10th ed. Philadelphia, PA: Elsevier;2021:chap 2.