A Meal Delivery and Exercise Intervention to Increase Resilience in Homebound Older Adults
Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The purpose of this study is to evaluate the effects of a home-based exercise program administered through Meals on wheels (MOW) on gait speed and frailty status and to assess the association between novel serum biomarkers (70 kilodalton heat shock proteins (HSP70),Macrophage Inflammatory Proteins(MIP1b), soluble IL-6 receptor alpha-chain (sIL-6R)) and established but non-specific frailty biomarkers (Interleukin 6 (IL-6), C-reactive protein (CRP), Tumor necrosis factor (TNF-α)) in frail and prefrail homebound older adults before and after the exercise intervention.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 60
Healthy Volunteers: f
View:
• homebound (normally unable to leave the home unassisted)
• frail or prefrail by The Fried Frailty Phenotype (FFP)
• medically stable
Locations
United States
Texas
The University of Texas Health Science Center at Houston
RECRUITING
Houston
Contact Information
Primary
Jessica Lee, MD,MS
Jessica.Lee@uth.tmc.edu
713-500-5457
Backup
Paola Robles Cordova
Paola.RoblesCordova@uth.tmc.edu
(713) 500-7904
Time Frame
Start Date: 2021-07-19
Estimated Completion Date: 2026-02-28
Participants
Target number of participants: 100
Treatments
Experimental: Meals plus exercise
Experimental: Meals only
Related Therapeutic Areas
Sponsors
Collaborators: National Institute on Aging (NIA)
Leads: The University of Texas Health Science Center, Houston