Study of the Effect of Sevoflurane General Anesthetic on Spatial Memory in Humans
Status: Recruiting
Location: See all (2) locations...
Intervention Type: Procedure
Study Type: Observational
SUMMARY
The goal of this observational study is to learn about the effect of general anesthetic on spatial memory in adults who will undergo to an elective surgery. The main question it aims to answer is: • A surgical event under general anesthesia with sevoflurane transiently impairs spatial memory in humans and induces an increase in inflammatory cytokines. Participants will perform a virtual maze test and plasma samples will be taken before and after surgery.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 30
Maximum Age: 50
View:
• Candidate for elective laparoscopic surgery of cholecystectomy.
• Age 30 to 50 years.
Locations
Other Locations
Chile
Centro de Investigación Cínica Avanzada (CICA), Hospital Clinico de la Universidad de Chile
RECRUITING
Santiago
Hospital Clinico de la Universidad de Chile
RECRUITING
Santiago
Contact Information
Primary
Antonello Penna, MD, PhD
apenna@uchile.cl
+56956766623
Backup
Khaleed Etchegaray
khaleed.etchegaray@gmail.com
+56973310929
Time Frame
Start Date: 2023-08-14
Estimated Completion Date: 2025-12-30
Participants
Target number of participants: 22
Treatments
Adults 30-50 years
Related Therapeutic Areas
Sponsors
Leads: University of Chile