Peripheral Nerve Block in Patients With Painful Diabetic Polyneuropathy: How Important is the Peripheral Signaling?
Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The purpose of the present study is to evaluate the role of peripheral afferent input for spontaneous pain in painful diabetic polyneuropathy
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Aged 18 years or older.
• Probably diabetic neuropathy confirmed using the Toronto criteria in a conservative manner, i.e. three out of three symptoms/signs of neuropathy must be present (sensory neuropathy symptoms, distal reduced sensibility, reduced ankle reflexes) 7.
• Definite or probable neuropathic pain for minimum the last 6 months
• Mean pain intensity at \> 4 NRS the last week17.
⁃ Since we expect a large effect of the block it is not necessary to discontinue pain medication.
Locations
Other Locations
Denmark
Danish Pain Research Center, Aarhus University, Aarhus University Hospital
RECRUITING
Aarhus N
Contact Information
Primary
Ellen L Schaldemose, MD
ells@clin.au.dk
+45 93501942
Time Frame
Start Date: 2020-09-08
Estimated Completion Date: 2026-12-31
Participants
Target number of participants: 16
Treatments
Active_comparator: Xylocaine
Nerve block
Placebo_comparator: Isotonic saline
Nerve block
Related Therapeutic Areas
Sponsors
Leads: University of Aarhus