Randomized Double-blind Study of RTMS Analgesic Effect in Chronic Neuropathic Pain. Comparison Between Three Groups: Motor Cortex Stimulation by the Classic Coil B65, Deeper Stimulation by the Coil B70 and Placebo Stimulation. Analysis of Long-term RTMS-induced Brain Changes Using FMRI.
Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The purpose of this study is to compare the analgesic effectiveness of three modes of repetitive Transcranial Magnetic Stimulation (rTMS) in chronic neuropathic pain: * Classical rTMS stimulation * Deeper rTMS stimulation * Sham rTMS stimulation
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: f
View:
• Patient's written consent
• Affiliated with social security system
• Male or female, suffering for more than a year from unilateral refractory neuropathic pain: hemi-body, upper limb, lower limb and facial chronic pain.
• Patient whose analgesic treatment, is stable for at least 1 month.
• Patient not responding to conventional treatments
• Prescreening EVN \>3
Locations
Other Locations
France
Centre de la douleur, CHU Grenoble Alpes
RECRUITING
Grenoble
Contact Information
Primary
Hasan HODAJ, MD
HHodaj@chu-grenoble.fr
04-76-76-52-13
Time Frame
Start Date: 2021-07-16
Estimated Completion Date: 2025-12-01
Participants
Target number of participants: 45
Treatments
Experimental: Classic rTMS Stimulation using the B65 Coil
Experimental: Deeper rTMS Stimulation using the B70 Coil
Sham_comparator: control group with a sham stimulation using a sham coil
Related Therapeutic Areas
Sponsors
Leads: University Hospital, Grenoble