Deep Brain Stimulation for Refractory Trigeminal Neuralgia with a Pontine Lesion: a Pilot Study

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Phase 1
SUMMARY

The aim of this study is to assess the feasibility of deep brain stimulation for refractory trigeminal neuralgia due to a pontine lesion, as is usually seen in the context of multiple sclerosis. These patients usually have severe intractable facial pain and current medical and surgical options generally fail to achieve long lasting pain relief. Hoping to improve pain control in this population, the investigators of this trial propose a novel technique consisting of implanting a deep brain stimulation lead within the pontine lesion to modulate the generation of pain signals.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Adults of at least 18 years old

• Refractory trigeminal neuralgia : failure of at least 3 drugs and at least two lesioning surgical interventions (radiosurgery, percutaneous rhizotomy, or open rhizotomy).

• Pontine lesion proved by MRI in contact with trigeminal nerve tract

Locations
Other Locations
Canada
Centre Hospitalier Universitaire de Sherbrooke (CHUS)
RECRUITING
Sherbrooke
Contact Information
Primary
Christian Iorio-Morin, MD, PhD, FRCS(C)
Christian.Iorio-Morin@usherbrooke.ca
819-346-1110
Time Frame
Start Date: 2024-10-15
Estimated Completion Date: 2026-10
Participants
Target number of participants: 6
Treatments
Experimental: Deep brain stimulation
Implantation of deep brain stimulation lead within the pontine lesion
Sponsors
Leads: Université de Sherbrooke

This content was sourced from clinicaltrials.gov