Neuroendocrine Tumor
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Neuroendocrine Tumor Overview

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Learn About Neuroendocrine Tumor

What is the definition of Neuroendocrine Tumor?
Neuroendocrine tumors are rare cancers that grow from neuroendocrine cells. Neuroendocrine cells receive signals from the nervous system to release hormones. There are several types of neuroendocrine tumors, although most occur in the lungs, pancreas, adrenal glands, small intestine, appendix, and rectum. Neuroendocrine tumors may also spread to the lymph nodes, liver, or bones.
What are the symptoms of Neuroendocrine Tumor?
Symptoms of a neuroendocrine tumor depend on the tumor’s location and whether it is producing excess hormones. Symptoms of neuroendocrine tumors may include pain, a lump under the skin, fatigue, persistent cough or hoarseness, unexplained weight loss, confusion, anxiety, dizziness, shakiness, elevated blood glucose, low blood glucose, an ulcer, skin flushing, skin rash, increased thirst, nausea and vomiting, diarrhea, and carcinoid syndrome. Carcinoid syndrome is a condition that occurs when a neuroendocrine tumor produces excess hormones. Symptoms of carcinoid syndrome include skin flushing of the head and neck; sweating; shortness of breath; wheezing; rapid heartbeat; heart murmur; high blood pressure; yellowing of the skin and eyes; abdominal cramping; diarrhea; greasy, foul-smelling bowel movements; and swelling of the feet and legs.
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What are the current treatments for Neuroendocrine Tumor?
Treatment for neuroendocrine tumors depends on the type and location, as well as whether the tumor is producing excess hormones. Treatment for endocrine tumors may include surgery; chemotherapy; targeted drug therapy, such as everolimus and sunitinib; immunotherapy, such as interferon alfa-2b; peptide receptor radionuclide therapy; somatostatin analogs, such as octreotide and lanreotide; radiation therapy; radiofrequency ablation; and hepatic artery embolization.
Who are the top Neuroendocrine Tumor Local Doctors?
Elite in Neuroendocrine Tumor
Dr. Daniel M. Halperin
Family Medicine
Elite in Neuroendocrine Tumor
Dr. Daniel M. Halperin
Family Medicine

Emory At Mountain Park - Primary Care Suite 104

4120 Five Forks Trickum Road Southwest, Ste104, 
Lilburn, GA 
770-935-9546
Experience:
21+ years
Languages Spoken:
English
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Daniel Halperin is a Family Medicine provider practicing medicine in Lilburn, Georgia. He has been practicing medicine for over 21 years. Dr. Halperin is rated as an Elite provider by MediFind in the treatment of Neuroendocrine Tumor. He is also highly rated in 15 other conditions, according to our data. His clinical expertise encompasses Neuroendocrine Tumor, Carcinoid Syndrome, Pancreatic Islet Cell Tumor, Pancreaticoduodenectomy, and Colonoscopy. Dr. Halperin is board certified in American Board Of Family Medicine, 2008.

Elite in Neuroendocrine Tumor
Dr. Diane Reidy
Hematology Oncology | Hematology | Oncology
Elite in Neuroendocrine Tumor
Dr. Diane Reidy
Hematology Oncology | Hematology | Oncology

Duke Cancer Center

20 Duke Medicine Cir, 
Durham, NC 
919-681-6900
Languages Spoken:
English
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Offers Telehealth

Diane Reidy is a Hematologist Oncology specialist and a Hematologist practicing medicine in Durham, North Carolina. Dr. Reidy is rated as an Elite provider by MediFind in the treatment of Neuroendocrine Tumor. She is also highly rated in 18 other conditions, according to our data. Her clinical expertise encompasses Neuroendocrine Tumor, Pancreatic Islet Cell Tumor, Pancreatic Cancer, Pancreaticoduodenectomy, and Liver Embolization.

 
 
 
 
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Elite in Neuroendocrine Tumor
Dr. Shishir K. Maithel
Surgical Oncology
Elite in Neuroendocrine Tumor
Dr. Shishir K. Maithel
Surgical Oncology
675 N St Clair St Ste 21-100, Galter Pavilion, 
Chicago, IL 
866-587-4322
Experience:
26+ years
Languages Spoken:
English
See accepted insurances
Offers Telehealth

Shishir Maithel is a Surgical Oncologist practicing medicine in Chicago, Illinois. He has been practicing medicine for over 26 years. Dr. Maithel is rated as an Elite provider by MediFind in the treatment of Neuroendocrine Tumor. He is also highly rated in 29 other conditions, according to our data. His clinical expertise encompasses Cholangiocarcinoma (Bile Duct Cancer), Gallbladder Cancer, Pancreatic Islet Cell Tumor, Pancreaticoduodenectomy, and Hepatectomy. Dr. Maithel is board certified in American Board Of Surgery - Surgery (Certified).

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What are the latest Neuroendocrine Tumor Clinical Trials?
A Phase III Multi-center, Randomized, Open-label Study to Evaluate the Efficacy and Safety of [177Lu]Lu-DOTA-TATE in Patients Newly Diagnosed With Grade 1 and Grade 2 (Ki-67 <10%) Advanced GEP-NET With High Disease Burden (NETTER-3)
A Phase III Multi-center, Randomized, Open-label Study to Evaluate the Efficacy and Safety of [177Lu]Lu-DOTA-TATE in Patients Newly Diagnosed With Grade 1 and Grade 2 (Ki-67 <10%) Advanced GEP-NET With High Disease Burden (NETTER-3)
Enrollment Status: Recruiting
Publish Date: April 16, 2026
Intervention Type: Drug, Radiation
Study Phase: Phase 3

Summary: The purpose of the current study is to evaluate the efficacy and safety of \[177Lu\]Lu-DOTA-TATE plus octreotide long-acting release (LAR) versus octreotide LAR alone in newly diagnosed patients with somatostatin receptor positive (SSTR+), well differentiated Grade1 and Grade 2 (G1 and G2) (Ki-67 \<10%) advanced gastroenteropancreatic neuroendocrine tumors (GEP-NETs) with high disease burden

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A UGT1A1 Genotype-Directed Study of Belinostat Pharmacokinetics and Toxicity
A UGT1A1 Genotype-Directed Study of Belinostat Pharmacokinetics and Toxicity
Enrollment Status: Recruiting
Publish Date: April 16, 2026
Intervention Type: Drug
Study Phase: Phase 2

Background: High-grade neuroendocrine carcinomas (HGNEC) are cancers that develop in different parts of the body, including the digestive tract, genitals, neck, and head. One drug (belinostat), combined with 2 other drugs (etoposide and cisplatin), is approved to treat HGNEC. But some people may have a gene variant that affects how quickly their body gets rid of the drug; these people may do better with diffe...

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