68Ga-HA-DOTATATE Imaging of Suspected Somatostatin Receptor Positive Tumors

Who is this study for? Patients with suspected somatostatin receptor positive tumors
What treatments are being studied? 68Ga-HA-DOTATATE
Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 2
SUMMARY

Somatostatin receptor (SSR) imaging is a critical component of clinical care for many patients being investigated for or with confirmed SSR positive tumors. In the past, 111In-octreotide imaging has been used for this purpose but it has been recently supplanted globally by SSR positron emission tomography (PET) imaging due to better image quality and higher diagnostic accuracy. This study will assess the safety and diagnostic effectiveness of 68Ga-HA-DOTATATE produced a the Edmonton Radiopharmaceutical Centre (ERC).

Eligibility
Participation Requirements
Sex: All
Healthy Volunteers: f
View:

• Patients with known or clinically suspected somatostatin receptor positive tumors including but not limited to: gastrointestinal neuroendocrine tumors, pancreatic neuroendocrine tumors, pulmonary neuroendocrine tumors, neuroendocrine tumors - primary unknown, pheochromocytoma, paraganglioma, medullary thyroid cancer, medulloblastoma, meningioma

• A standard clinical CT or MRI is obtained within 6 months of enrollment

• Ability to provide written informed consent prior to participation in the study (participant or if required a legal medical decision maker)

Locations
Other Locations
Canada
University of Alberta
RECRUITING
Edmonton
Contact Information
Primary
Jonathan Abele, MD
jabele@ualberta.ca
780-407-6907
Time Frame
Start Date: 2022-02-15
Estimated Completion Date: 2028-08-31
Participants
Target number of participants: 600
Treatments
Experimental: 68Ga-HA-DOTATATE PET/CT scan
2.64 MBq/kg (minimum 37 MBq, maximum 250 MBq) 68Ga-HA-DOTATATE intravenous single-dose administration for PET/CT imaging
Related Therapeutic Areas
Sponsors
Leads: University of Alberta

This content was sourced from clinicaltrials.gov