Neuronal Intranuclear Inclusion Disease (NIID)
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Neuronal Intranuclear Inclusion Disease (NIID) Overview

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Learn About Neuronal Intranuclear Inclusion Disease (NIID)

What is the definition of Neuronal Intranuclear Inclusion Disease (NIID)?
Neuronal intranuclear inclusion disease (NIID) is a slowly progressive, neurodegenerative disease. NIID may affect any part of the nervous system (central, peripheral, and/or autonomic), as well as various organs. Therefore, people with NIID may have impairment of balance, movement, cognition, communication, behavior, and the ability to function independently. In general, limb weakness and ataxia are more common in children with NIID, while dementia is more common in people diagnosed in adulthood. The features of NIID result from the presence of eosinophilic intranuclear inclusions inside neurons and glial cells (abnormal masses of substances in the nuclei of cells of the nervous system). Recently, a genetic change in the NOTCH2NLC gene has been found to cause NIID.
What are the alternative names for Neuronal Intranuclear Inclusion Disease (NIID)?
  • Neuronal intranuclear inclusion disease
  • NIID
  • Neuronal intranuclear hyaline inclusion disease
Who are the top Neuronal Intranuclear Inclusion Disease (NIID) Local Doctors?
Distinguished in Neuronal Intranuclear Inclusion Disease (NIID)
Dr. Daniel L. Murman
Neurology
Distinguished in Neuronal Intranuclear Inclusion Disease (NIID)
Dr. Daniel L. Murman
Neurology

Neurological Sciences Center At Clarkson Doctors Building North

4242 Farnam St., Suite 650, 
Omaha, NE 
402-559-8600
Experience:
37+ years
Languages Spoken:
English
See accepted insurances
Offers Telehealth

Daniel Murman is a Neurologist practicing medicine in Omaha, Nebraska. He has been practicing medicine for over 37 years. Dr. Murman is rated as a Distinguished provider by MediFind in the treatment of Neuronal Intranuclear Inclusion Disease (NIID). He is also highly rated in 19 other conditions, according to our data. His clinical expertise encompasses Alzheimer's Disease, Dementia, Primary Progressive Aphasia, and Frontotemporal Dementia.

Advanced in Neuronal Intranuclear Inclusion Disease (NIID)
Dr. Darren Gitelman
Psychology
Advanced in Neuronal Intranuclear Inclusion Disease (NIID)
Dr. Darren Gitelman
Psychology

Advocate Memory Center

1875 Dempster St, Ste 520, 
Park Ridge, IL 
847-720-6464
Languages Spoken:
English
See accepted insurances
Offers Telehealth

Darren Gitelman is a Psychologist practicing medicine in Park Ridge, Illinois. Dr. Gitelman is rated as an Advanced provider by MediFind in the treatment of Neuronal Intranuclear Inclusion Disease (NIID). He is also highly rated in 6 other conditions, according to our data. His clinical expertise encompasses Alzheimer's Disease, Dementia, Cerebellar Degeneration, and Memory Loss. Dr. Gitelman is board certified in American Board Of Internal Medicine.

 
 
 
 
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Advanced in Neuronal Intranuclear Inclusion Disease (NIID)
Dr. Syed S. Hyder
Neurology
Advanced in Neuronal Intranuclear Inclusion Disease (NIID)
Dr. Syed S. Hyder
Neurology

Ballad Health Medical Associates Neurology

1406 Tusculum Boulevard, Suite 1200, 
Greeneville, TN 
423-631-0543
Languages Spoken:
English
See accepted insurances
Offers Telehealth

. Dr. Hyder is rated as an Advanced provider by MediFind in the treatment of Neuronal Intranuclear Inclusion Disease (NIID). He is also highly rated in 11 other conditions, according to our data. His clinical expertise encompasses Generalized Tonic-Clonic Seizure, Seizures, Parkinson's Disease, and Movement Disorders. Dr. Hyder is board certified in  .

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Who are the sources who wrote this article ?

Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center

What are the Latest Advances for Neuronal Intranuclear Inclusion Disease (NIID)?
Recurrent Bilateral Macular Edema Linked to NOTCH2NLC GGC Repeat Expansion: A Case Report.
Recurrent Bilateral Macular Edema Linked to NOTCH2NLC GGC Repeat Expansion: A Case Report.
Journal: The American journal of case reports
Published: April 11, 2026
Astrocyte-vascular interactions are disturbed in cerebral white matter of adult-onset neuronal intranuclear inclusion disease.
Astrocyte-vascular interactions are disturbed in cerebral white matter of adult-onset neuronal intranuclear inclusion disease.
Journal: Journal of neuropathology and experimental neurology
Published: February 06, 2026
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Teaching NeuroImage: an imaging clue for neuronal intranuclear inclusion disease.
Teaching NeuroImage: an imaging clue for neuronal intranuclear inclusion disease.
Journal: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
Published: January 27, 2026
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