Neuronal Intranuclear Inclusion Disease (NIID)
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Neuronal Intranuclear Inclusion Disease (NIID) Overview

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Learn About Neuronal Intranuclear Inclusion Disease (NIID)

What is the definition of Neuronal Intranuclear Inclusion Disease (NIID)?
Neuronal intranuclear inclusion disease (NIID) is a slowly progressive, neurodegenerative disease. NIID may affect any part of the nervous system (central, peripheral, and/or autonomic), as well as various organs. Therefore, people with NIID may have impairment of balance, movement, cognition, communication, behavior, and the ability to function independently. In general, limb weakness and ataxia are more common in children with NIID, while dementia is more common in people diagnosed in adulthood. The features of NIID result from the presence of eosinophilic intranuclear inclusions inside neurons and glial cells (abnormal masses of substances in the nuclei of cells of the nervous system). Recently, a genetic change in the NOTCH2NLC gene has been found to cause NIID.
What are the alternative names for Neuronal Intranuclear Inclusion Disease (NIID)?
  • Neuronal intranuclear inclusion disease
  • NIID
  • Neuronal intranuclear hyaline inclusion disease
Who are the top Neuronal Intranuclear Inclusion Disease (NIID) Local Doctors?
Darren Gitelman
Advanced in Neuronal Intranuclear Inclusion Disease (NIID)
Dr. Darren Gitelman
Psychology
Advanced in Neuronal Intranuclear Inclusion Disease (NIID)
Dr. Darren Gitelman
Psychology

Advocate Memory Center

1875 Dempster St, Ste 520, 
Park Ridge, IL 
847-720-6464
Languages Spoken:
English
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Darren Gitelman is a Psychologist in Park Ridge, Illinois. Dr. Gitelman is rated as an Advanced provider by MediFind in the treatment of Neuronal Intranuclear Inclusion Disease (NIID). His top areas of expertise are Alzheimer's Disease, Dementia, Cerebellar Degeneration, and Memory Loss.

Syed S. Hyder
Advanced in Neuronal Intranuclear Inclusion Disease (NIID)
Dr. Syed S. Hyder
Neurology
Advanced in Neuronal Intranuclear Inclusion Disease (NIID)
Dr. Syed S. Hyder
Neurology

Ballad Health Medical Associates Neurology

1406 Tusculum Boulevard, Suite 1200, 
Greeneville, TN 
423-631-0543
Languages Spoken:
English
See accepted insurances
Offers Telehealth

. Dr. Hyder is rated as an Advanced provider by MediFind in the treatment of Neuronal Intranuclear Inclusion Disease (NIID). His top areas of expertise are Generalized Tonic-Clonic Seizure, Seizures, Parkinson's Disease, and Movement Disorders.

 
 
 
 
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Elite in Neuronal Intranuclear Inclusion Disease (NIID)
Hiroyuki Ishiura
Elite in Neuronal Intranuclear Inclusion Disease (NIID)
Hiroyuki Ishiura
Okayama, JP 

Hiroyuki Ishiura practices in Okayama, Japan. Mr. Ishiura is rated as an Elite expert by MediFind in the treatment of Neuronal Intranuclear Inclusion Disease (NIID). His top areas of expertise are Neuronal Intranuclear Inclusion Disease (NIID), Paraplegia, Spastic Paraplegia Type 7, Acute Cerebellar Ataxia, and Bone Marrow Transplant.

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Who are the sources who wrote this article ?

Published Date: May 02, 2022
Published By: Genetic and Rare Diseases Informnation Center

What are the Latest Advances for Neuronal Intranuclear Inclusion Disease (NIID)?
Biomarkers.
Biomarkers.
Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association
Published: December 25, 2025
Biomarkers.
Biomarkers.
Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association
Published: December 25, 2025
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Basic Science and Pathogenesis.
Basic Science and Pathogenesis.
Journal: Alzheimer's & dementia : the journal of the Alzheimer's Association
Published: December 23, 2025
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