Complex Lifestyle Modification in the Treatment of Non-alcoholic Fatty Liver Disease
Status: Recruiting
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY
The project will study the impact of individually tailored lifestyle counselling compared to standard care on the parameters of NAFLD/NASH in patients with metabolic syndrome. The factors affecting the outcome (including clinical and laboratory parameters and microbiome profiling) will be evaluated.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:
• Individuals with NAFLD and metabolic syndrome
Contact Information
Primary
Radan Bruha, Prof.
bruha@cesnet.cz
+420224962506
Backup
Vaclav Smid, MD
vaclav.smid@vfn.cz
+420224962506
Time Frame
Start Date: 2023-08-30
Estimated Completion Date: 2026-12
Participants
Target number of participants: 100
Treatments
Experimental: Professional lifestyle modification counselling (behavioral therapy)
Lifestyle intervention will be based on CBT (cognitive behavioral therapy) and mindfulness, especially mindful eating by professional organisation STOB.
No_intervention: standard care
Patients will have standard care with regular visits at an outpatient Department of Hepatology. Standard recommendations of lifestyle change and weight reduction will be given by hepatologists.
Related Therapeutic Areas
Sponsors
Leads: General University Hospital, Prague