Disease Mechanisms and Markers for Non-alcoholic Steatohepatitis in a Population With Non-alcoholic Fatty Liver Disease: a Prospective Cohort Study With Biobank
Status: Recruiting
Location: See location...
Study Type: Observational
SUMMARY
The aim of the present prospective NAFLD cohort study (with biobank), of obese subjects with proven NAFLD based on liver biopsy and/or MRI, is to study factors contributing to the development of NASH in patients with simple steatosis and to identify and validate non-invasive markers for the diagnosis of NASH.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 65
Healthy Volunteers: f
View:
• NAFLD diagnosis based on evidence of hepatic steatosis, either by imaging (using MRI) or by histology.
• BMI ≥ 30 kg/m2
• Between 18 - 65 years of age
Locations
Other Locations
Netherlands
Maastricht University Medical Center
RECRUITING
Maastricht
Contact Information
Primary
Koek, MD, PhD
0031-43-3875021
Time Frame
Start Date: 2015-06
Estimated Completion Date: 2027-12
Participants
Target number of participants: 500
Related Therapeutic Areas
Sponsors
Leads: Maastricht University Medical Center
Collaborators: Centrum Obesitas-Eetstoornissen (CO-EUR)