Condition 101 About Nonbacterial Prostatitis

What is the definition of Nonbacterial Prostatitis?

Chronic nonbacterial prostatitis causes long-term pain and urinary symptoms. It involves the prostate gland or other parts of a man's lower urinary tract or genital area. This condition is not caused by an infection with bacteria.

What are the alternative names for Nonbacterial Prostatitis?

NBP; Prostatodynia; Pelvic pain syndrome; CPPS; Chronic nonbacterial prostatitis; Chronic genitourinary pain

What are the causes for Nonbacterial Prostatitis?

Possible causes of nonbacterial prostatitis include:

  • A past bacterial prostatitis infection
  • Bicycle riding
  • Less common types of bacteria
  • Irritation caused by a backup of urine flowing into the prostate
  • Irritation from chemicals
  • Nerve problem involving the lower urinary tract
  • Parasites
  • Pelvic floor muscle problem
  • Sexual abuse
  • Viruses

Life stresses and emotional factors may play a part in the problem.

Most men with chronic prostatitis have the nonbacterial form.

What are the symptoms for Nonbacterial Prostatitis?

Symptoms may include:

  • Blood in the semen
  • Blood in the urine
  • Pain in the genital area and lower back
  • Pain with bowel movements
  • Pain with ejaculation
  • Problems with urinating

What are the current treatments for Nonbacterial Prostatitis?

Treatment for nonbacterial prostatitis is difficult. The problem is hard to cure, so the goal is to control symptoms.

Several types of medicines may be used to treat the condition. These include:

  • Long-term antibiotics to make sure that the prostatitis is not caused by bacteria. However, people who are not helped by antibiotics should stop taking these medicines.
  • Drugs called alpha-adrenergic blockers help relax the muscles of the prostate gland. It often takes about 6 weeks before these medicines start working. Many people do not get relief from these medicines.
  • Aspirin, ibuprofen, and other nonsteroidal anti-inflammatory drugs (NSAIDs), which may relieve symptoms for some men.
  • Muscle relaxers like diazepam or cyclobenzaprine can help to reduce spasms in the pelvic floor.

Some people have found some relief from pollen extract (Cernitin) and allopurinol. But research does not confirm their benefit. Stool softeners may help reduce discomfort with bowel movements.

Surgery, called transurethral resection of the prostate, may be done in rare cases if medicine does not help. In most cases, this surgery is not done on younger men. It may cause retrograde ejaculation. This can lead to sterility, impotence, and incontinence.

Other treatments that may be tried include:

  • Warm baths to ease some of the pain
  • Prostate massage, acupuncture, and relaxation exercises
  • Dietary changes to avoid bladder and urinary tract irritants
  • Pelvic floor physical therapy

What is the outlook (prognosis) for Nonbacterial Prostatitis?

Many people respond to treatment. However, others do not get relief, even after trying many things. Symptoms often come back and may not be treatable.

What are the possible complications for Nonbacterial Prostatitis?

Untreated symptoms of nonbacterial prostatitis may lead to sexual and urinary problems. These problems can affect your lifestyle and emotional well-being.

When should I contact a medical professional for Nonbacterial Prostatitis?

Call your health care provider if you have symptoms of prostatitis.



Carter C. Urinary tract disorders. In: Rakel RE, Rakel DP, eds. Textbook of Family Medicine. 9th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 40.

Kaplan SA. Benign prostatic hyperplasia and prostatitis. In: Goldman L, Schafer AI, eds. Goldman-Cecil Medicine. 26th ed. Philadelphia, PA: Elsevier; 2020:chap 120.

McGowan CC. Prostatitis, epididymitis, and orchitis. In: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 9th ed. Philadelphia, PA: Elsevier; 2020:chap 110.

Nickel JC. Inflammatory and pain conditions of the male genitourinary tract: prostatitis and related pain conditions, orchitis, and epididymitis. In: Wein AJ, Kavoussi LR, Partin AW, Peters CA, eds. Campbell-Walsh Urology. 11th ed. Philadelphia, PA: Elsevier; 2016:chap 13.

Top Global Doctors For Nonbacterial Prostatitis

Mikio Sugimoto
Michiko Oka
Kyoto, JP
Jenni Bernoulli
Turku, FI
Yoshiyuki Kakehi
Ikenobe, JP
Emrah Yatkin
Turku, FI
Song Fan
Hefei, CN

Latest Advances On Nonbacterial Prostatitis

  • Condition: Kidney-Yang Deficiency Type Chronic Non-Bacterial Prostatitis (CNP)
  • Journal: Zhen ci yan jiu = Acupuncture research
  • Treatment Used: Acupuncture of Sanhuang Points
  • Number of Patients: 60
  • Published —
This study observed the clinical effect of acupuncture stimulation of Sanhuang points in the treatment of kidney-yang deficiency chronic non-bacterial prostatitis (CNP).
  • Condition: Chronic Prostatitis
  • Journal: Urologiia (Moscow, Russia : 1999)
  • Treatment Used: Longidaza
  • Number of Patients: 18
  • Published —
This study tested the safety and efficacy of using longidaza to treat chronic inflammation of the prostate.

Clinical Trials For Nonbacterial Prostatitis

There are no recent clinical trials available for this condition. Please check back because new trials are being conducted frequently.