Phenotypes, Biomarkers and Pathophysiology in INPH
Status: Recruiting
Location: See location...
Intervention Type: Other, Diagnostic test
Study Type: Observational
SUMMARY
The aim of this study is to determine the clinical spectrum and natural progression of idiopathic normal pressure hydrocephalus （iNPH ) and related disorders in a prospective single center study, identify digital, imaging and molecular biomarkers that can assist in diagnosis and therapy development and study the etiology and molecular mechanisms of these diseases.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 80
Healthy Volunteers: t
View:
• patients who was diagnosed as idiopathic normal pressure hydrocephalus
Locations
Other Locations
China
Fengzeng Jian
RECRUITING
Beijing
Contact Information
Primary
fengzeng jian, md
jianfengzeng@xwh.ccmu.edu.cn
01083198899
Backup
xin qu, md
xinqu@xwhosp.org
01083198899
Time Frame
Start Date: 2024-05-15
Estimated Completion Date: 2027-05
Participants
Target number of participants: 200
Treatments
hydrocephalus
high throughput sequencing and electromyography Whole Genome Sequencing, Whole Exome Sequencing, Transcriptomics, Proteomics, Metabolomics and imaging, such as DTIALPS
Normal group
Whole Genome Sequencing, Whole Exome Sequencing, Transcriptomics, Proteomics, Metabolomics
Related Therapeutic Areas
Sponsors
Leads: Xuanwu Hospital, Beijing