Obesity in Children Clinical Trials

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Trading Sugar for Sparkles in Adolescents, A Sensory Approach for Reducing Added Sugar From Sweetened Beverages

Status: Recruiting
Location: See all (3) locations...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this clinical trial is to test whether replacing sugary sodas with unsweetened, flavored sparkling waters can reduce added sugar intake and improve health in Black/African American and Latine adolescents with obesity who prefer sweet-tasting beverages. The main questions it aims to answer are: * Does replacing sugary sodas with water change liking for sugary drinks, and water? * Do shifts in liking for sweetness lead to improved diet quality and cardiometabolic health? Researchers will compare replacing sugary sodas with one of three alternative beverages: unsweetened sparkling water, plain water, and beverages with gradually reduced sugar to determine which strategy is most effective. Participants will: * Replace sugary sodas with study drinks for 4 weeks * Complete taste tests to measure their liking for and sensory experience of sweetness over 8-weeks * Provide dietary recalls, body measurements, and blood samples over 8-weeks

Eligibility
Participation Requirements
Sex: All
Minimum Age: 12
Maximum Age: 18
Healthy Volunteers: t
View:

• Adolescents ages 12 to 18 who display a sweet-liker pattern, characterized by a preference for higher concentrations of sugar in beverages, specifically identifying 0.3M (10.3% sucrose) or above as their most liked sample.

• Adolescents consumes sugar-sweetened soda greater than or equal to 2 times per week. Adolescents must also indicate a willingness to drink study beverages; not currently dieting/changing diet.

Locations
United States
Indiana
Indiana University School of Public Health - Bloomington
NOT_YET_RECRUITING
Bloomington
Indiana University Hospital
RECRUITING
Indianapolis
Purdue University
RECRUITING
West Lafayette
Contact Information
Primary
Nana Gletsu Miller, PhD
ngletsum@iu.edu
+1 (812) 855-9110
Time Frame
Start Date: 2025-07-25
Estimated Completion Date: 2027-06
Participants
Target number of participants: 63
Treatments
Experimental: Unsweetened Sparkling Water (USW)
Participants in this group will replace all sugar-sweetened sodas with flavored, unsweetened sparkling waters for 4 weeks.
Experimental: Progressively Reduced Sugar (PRS)
Participants in this group will replace sugar-sweetened sodas with carbonated beverages that contain decreasing levels of sugar each week over a 4-week period, ending with a fully unsweetened sparkling water.
Active_comparator: Plain Water (PW)
Participants in this group will replace all sugar-sweetened sodas with plain, still water for 4 weeks. This arm serves as a control to compare outcomes against both the unsweetened sparkling water and gradually reduced sugar beverage interventions.
Related Therapeutic Areas
Sponsors
Leads: Nana Gletsu Miller
Collaborators: Purdue University

This content was sourced from clinicaltrials.gov