Bioactive Dairy Lipids to Manage Cardiometabolic Risk in Obesity
It is a randomized parallel arm intervention study in adults with severe obesity. The objective is to demonstrate that within a dietary handling for weight loss, the daily ingestion during 3 months of whole dairy products enriched with milk polar lipids or whole dairy products decreases to a greater extent fasting plasma apolipoprotein B concentrations than the daily ingestion of low-fat dairy products (control group). Metabolic parameters will be assessed before and after the 3-month intervention, both at fasting and in postprandial period after the consumption of standardized meals.
• Men and women between 18-70 years
• Body Mass Index (BMI) between 35 and 60 kg/m2 inclusive
• Stable body weight (weight change +/- 5 % for 3 months prior to screening)
• Consumption of at least 1 serving/day of dairy products made from cow's milk
• Informed consent