Water Intake and Weight Control in Older Adults

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

This study is a randomized controlled intervention trial in adults aged 50+ years with overweight or obesity, which will compare three groups with different diet prescriptions: 1) pre-meal water consumption (500 ml, before each main meal) with a hypocaloric diet; 2) 1500 ml water consumed throughout the day with a hypocaloric diet; 3) hypocaloric diet with no instructions regarding water consumption. Smart water bottles will objectively assess water intake timing and volume. Urine osmolality, urine volume, and serum osmolality will be used as objective indicators of compliance with the water intake prescription. We will investigate changes in perceived hunger and fullness and appetite-regulating hormones as potential mechanisms by which premeal water could improve appetite regulation. We will also investigate the impact of water consumption and hydration on executive function capabilities, which may influence intervention adherence. Although increasing water intake could be an effective weight management strategy, no evidence-based recommendations exist for the timing of water intake needed for this benefit.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 50
Healthy Volunteers: t
View:

• aged 50+ years

• BMI ≥25 kg/m2

• weight stable (+/- 2 kg) in past 6 months

• willing to provide consent and comply with study protocol

Locations
United States
Virginia
Virginia Tech
RECRUITING
Blacksburg
Contact Information
Primary
Brenda Davy, PhD RDN
bdavy@vt.edu
540-231-6784
Backup
Elaina Marinik, PhD
emarinik@vt.edu
540-231-0923
Time Frame
Start Date: 2023-11-13
Estimated Completion Date: 2028-07-31
Participants
Target number of participants: 375
Treatments
Experimental: Pre-meal water + Hypocaloric diet
premeal water ( 500 ml) before each main meal, three times per day + hypocaloric diet
Experimental: Daily water + Hypocaloric diet
total daily water prescription (1500 ml/d) + hypocaloric diet
Active_comparator: Hypocaloric Diet alone
hypocaloric diet with not instructions regarding water intake
Related Therapeutic Areas
Sponsors
Leads: Virginia Polytechnic Institute and State University

This content was sourced from clinicaltrials.gov