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Impact of Yo-Yo Sleep on Cardiometabolic Health

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this clinical trial is to test the impact of repeated intermittent short sleep, with short sleep maintained 5 days per week followed by 2 days of prolonged sleep, compared to daily adequate sleep, on energy balance and cardiometabolic risk. A secondary goal of this research is to determine if maintaining a constant midpoint of sleep while undergoing intermittent short sleep, leads to better outcomes than intermittent short sleep with a 2-hour delay in sleep midpoint. The aims of this research will be tested in the context of a 3-group, parallel-arm, outpatient intervention of 4 weeks in duration, in young-to-middle-aged adults (aged 18-49 years).

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 49
Healthy Volunteers: t
View:

• Aged 18 to 49 years

• BMI 20-29.9 kg/m2

• Habitually sleeping 7-9 hours/night without sleep aids or naps

Locations
United States
New York
Columbia University Irving Medical Center
RECRUITING
New York
Contact Information
Primary
Marie-Pierre St-Onge, PhD
ms2554@cumc.columbia.edu
212-305-9549
Backup
Greiby Mercedes
gdm2130@cumc.columbia.edu
646-761-3455
Time Frame
Start Date: 2023-09-22
Estimated Completion Date: 2028-06
Participants
Target number of participants: 72
Treatments
Active_comparator: Stable Adequate Sleep (SAS)
Participants will go to bed and wake up at the same time every night, maintaining adequate sleep duration.
Experimental: ISS_Alone
Intermittent short sleep (ISS) 5 nights of 5.5 hours time in bed 2 nights of 9.5 hours time in bed with advanced bedtimes and delayed wake times
Experimental: ISS_SJL
Intermittent short sleep with short jetlag (SJL) 5 nights of 5.5 hours time in bed 2 nights of 9.5 hours time in bed with constant bedtimes and delayed wake times
Related Therapeutic Areas
Sponsors
Leads: Columbia University
Collaborators: Icahn School of Medicine at Mount Sinai, University of Colorado, Denver, National Heart, Lung, and Blood Institute (NHLBI)

This content was sourced from clinicaltrials.gov