Persea Americana for Total Health (PATH)-2

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this clinical trial is to learn about the effects of avocado consumption on gastrointestinal health in adults with overweight and obesity. The main questions is aims to answer are: How does avocado consumption affect the gut microbiome? How does avocado consumption affect thinking? Are there connections between the microbiome and cognition? Participants will be asked to eat provided meals with and without avocados for three 4-week periods. At the end of each 4-week period, participants will be asked to provide stool samples and complete computer games that assess thinking and memory.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 25
Maximum Age: 74
Healthy Volunteers: t
View:

• Participants must be between the ages of 25 and 74 years old

• BMI ≥ 25 kg/m2

• Ability to drop off fecal sample within 15 minutes of defecation

• 20/20 or corrected vision

Locations
United States
Illinois
University of Illinois, Urbana Champaign
RECRUITING
Urbana
Contact Information
Primary
Hannah D Holscher, PhD, RD
hholsche@illinois.edu
217-300-2512
Backup
Maggie Oleksiak, MS
maggieo4@illinois.edu
Time Frame
Start Date: 2023-07-11
Estimated Completion Date: 2024-07
Participants
Target number of participants: 45
Treatments
Experimental: Avocado
The experimental treatment will contain an avocado. Avocados will be consumed daily for 4 weeks.
Active_comparator: Fiber + Oil
The active comparator will have a snack that mimics the fiber and fatty acid composition found in avocados and will be consumed daily for 4 weeks.
Sham_comparator: Standard American Diet
The sham comparator contains foods and beverages of a standard American diet and will be consumed daily for 4 weeks.
Related Therapeutic Areas
Sponsors
Leads: University of Illinois at Urbana-Champaign

This content was sourced from clinicaltrials.gov