Modulating Energy Density in Time-Restricted Eating

Status: Recruiting
Location: See location...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this randomized controlled trial is to test the effect of time-restricted eating (14-hour fast, 10-hour eating window) of a low-energy dense diet (reduced calories per gram of food) in older adults with obesity and insulin resistance. The study aims to determine if modulating the energy density of the diet reduces: 1. Insulin resistance and 2. Body weight. Researchers will compare the groups: 1. Following time-restricted eating and given a diet reduced in energy density or 2. Following time-restricted eating and given a diet typically consumed in this population

Eligibility
Participation Requirements
Sex: All
Minimum Age: 50
Maximum Age: 75
Healthy Volunteers: f
View:

• Body mass index (BMI) ≥ 30kg/m2.

• Mini-Mental State Examination (MMSE) \> 25

• Geriatric Depression Scale-15 (GDS-15) \< 9

• Homeostatic model assessment of insulin resistance (HOMA-IR) ≥ 3.

Locations
United States
Louisiana
Pennington Biomedical Research Center
RECRUITING
Baton Rouge
Contact Information
Primary
Candida J Rebello, Ph.D.
Candida.Rebello@pbrc.edu
2252882411
Backup
Darryl Whitehead, BS
Darryl.Whitehead@pbrc.edu
Time Frame
Start Date: 2024-05-29
Estimated Completion Date: 2026-04
Participants
Target number of participants: 40
Treatments
Experimental: Low energy dense diet
Subjects will be required to follow time-restricted eating and receive a diet low in energy density
Active_comparator: Usual diet
Subjects will be required to follow time-restricted eating and receive the usual diet.
Related Therapeutic Areas
Sponsors
Leads: Pennington Biomedical Research Center

This content was sourced from clinicaltrials.gov