Beyond MARS: Magnetic Resonance Study: A Novel Assessment of Placental Perfusion During Pregnancy

Status: Recruiting
Location: See location...
Intervention Type: Diagnostic test
Study Type: Observational
SUMMARY

The purpose of this study is to evaluate the flow of oxygen and blood necessary for nutrient transfer across the placenta during the second and third trimesters in pregnancy in women who are obese before pregnancy compared to women who have an average weight before pregnancy. This study will evaluate blood flow across the placenta by functional Magnetic Resonance Imaging (fMRI) using arterial spin labeling (ASL). The investigators hypothesize that there will be differences in placental oxygenation and blood flow among women with obesity as compared to those with normal weight. Participants will be asked to complete Magnetic Resonance Imaging scans (MRIs), the first in the second trimester at 20-24 weeks and the second in the third trimester at 30-34 weeks.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 18
Maximum Age: 60
View:

• singleton pregnancy

Locations
United States
Illinois
NorthShore University HealthSystem
RECRUITING
Evanston
Contact Information
Primary
Kate Honeyfield
khoneyfield@northshore.org
(847) 570-2243
Backup
Caitlin A MacGregor
CMacgregor@northshore.org
(847) 570-4729
Time Frame
Start Date: 2024-05-09
Estimated Completion Date: 2026-12
Participants
Target number of participants: 30
Treatments
Normal Weight
Body Mass Index (BMI) 18.5-24.9 kg/m\^2
Obese
Pre-pregnancy Body Mass Index (BMI) ≥ 30.0 kg/m\^2
Related Therapeutic Areas
Sponsors
Leads: Endeavor Health

This content was sourced from clinicaltrials.gov

Similar Clinical Trials