Acute Effects of Animal Versus Plant-Based Protein Within a Realistic High-Fat Meal on Metabolic and Inflammatory Factors

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Shifting away from diets high in animal products towards more plant predominant diets is recommended by many health organizations to both reduce the negative environmental impacts of animal agriculture and to improve health outcomes. As a result, a number of plant-based meat alternatives such as Beyond Meat have been formulated to promote increased plant consumption. However, evidence is limited on the impact of newer plant-based meat alternatives on common cardiometabolic risk factors. The investigators aim to compare the acute metabolic, gastrointestinal, and inflammatory effects of a plant-based meat alternative (i.e., Beyond Meat) versus a comparable beef product within the context of high-fat, Western-style meal (i.e., eggs, meat, refined bread product). The investigators will also examine whether these responses differ based on whether individuals have a normal-weight or have overweight/obesity.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 50
Healthy Volunteers: t
View:

• 18 - 50 years.

• Body mass index \> 18.5 kg/m2

• Not pregnant (females only)

• Not postmenopausal (females only).

• Not been diagnosed with cardiovascular disease.

• Not been diagnosed with a cardiometabolic conditions (e.g., type 2 diabetes)

• Not been diagnosed with a chronic inflammatory condition (e.g., rheumatoid arthritis, inflammatory bowel disease).

• Does not regularly take anti-inflammatory drugs (more than 2x week).

• Does not use glucose-lowering drugs (e.g., metformin)

• Does not use lipid-lowering drugs (e.g., statins)

• Does not use tobacco products or any illicit drugs.

• Does not have a pacemaker.

• Can consume pea products (Beyond Meat is made from pea protein).

Locations
United States
Indiana
Health Professions Building, Ball State University
RECRUITING
Muncie
Contact Information
Primary
Bryant Keirns, PhD
bryant.keirns@bsu.edu
765-285-8356
Time Frame
Start Date: 2023-11-01
Estimated Completion Date: 2024-12-01
Participants
Target number of participants: 30
Treatments
Experimental: Meal Consumption with Beyond Meat
During the Beyond Meat arm, participants will consume a high-fat meal containing Beyond Meat (rather than beef). Meals will be otherwise identical.
Active_comparator: Meal Consumption with Beef
During the Beef arm, participants will consume a high-fat meal containing beef (rather than Beyond Meat). Meals will be otherwise identical.
Related Therapeutic Areas
Sponsors
Leads: Ball State University

This content was sourced from clinicaltrials.gov