Weight Maintenance in Adolescents With Obesity; Long-Term Treatment With Semaglutide s.c.2.4 mg Once-weekly
Status: Recruiting
Location: See all (102) locations...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 4
SUMMARY
The study is testing how well semaglutide can help adolescents with excess body weight to lose weight and to maintain weight loss. All participants in the study will receive semaglutide as a weekly injection. The study medicine is injected with a thin needle in the stomach, thighs or upper arms. All participants will get semaglutide treatment for a minimum of 3 years.
Eligibility
Participation Requirements
Sex: All
Minimum Age: 12
Maximum Age: 15
Healthy Volunteers: f
View:
• Informed consent obtained before any study-related activities. Study-related activities are any procedures that are carried out as part of the study, including activities to determine suitability for the study:
‣ The parent(s) or legally acceptable representative (LAR) of the participant must sign and date the Informed Consent Form, according to local requirements
⁃ The participant must sign and date the Child Assent Form or provide oral assent, according to local requirements
• Age 12 to less than 15 years at the time of signing the informed consent
• BMI greater than or equal to 95th percentile at screening
• Body weight greater than 60 kg at screening
Locations
United States
California
Neighborhood Healthcare
WITHDRAWN
Escondido
Florida
Clinical Neuroscience Solution
ACTIVE_NOT_RECRUITING
Orlando
TMH Physician Partners Endo
ACTIVE_NOT_RECRUITING
Tallahassee
Georgia
Children's Healthcare Atlanta
ACTIVE_NOT_RECRUITING
Atlanta
Columbus Research Foundation
ACTIVE_NOT_RECRUITING
Columbus
Eastside Bariatric and Gen Surg
ACTIVE_NOT_RECRUITING
Snellville
Iowa
University Of Iowa Hospitals and Clinics
ACTIVE_NOT_RECRUITING
Iowa City
Idaho
Solaris Clinical Research
ACTIVE_NOT_RECRUITING
Meridian
Illinois
Synexus Clinical Research US Inc.-Chicago
WITHDRAWN
Chicago
Indiana
Indiana University Hospital
WITHDRAWN
Indianapolis
Louisiana
Pennington Biom Res Ctr
ACTIVE_NOT_RECRUITING
Baton Rouge
Pennington Biom Res Ctr
RECRUITING
Baton Rouge
Maryland
Barry J. Reiner, MD LLC
ACTIVE_NOT_RECRUITING
Baltimore
Minnesota
University of Minnesota
ACTIVE_NOT_RECRUITING
Minneapolis
University of Minnesota
RECRUITING
Minneapolis
Mississippi
Mississippi CTR for ADV MED
WITHDRAWN
Madison
North Carolina
WakeMed Childn Endo-Dbt_Raleig
ACTIVE_NOT_RECRUITING
Raleigh
North Dakota
Valley Weight Loss Clinic
ACTIVE_NOT_RECRUITING
Fargo
Valley Weight Loss Clinic
RECRUITING
Fargo
New York
UBMD Peds-Div of Endo/Diabetes
ACTIVE_NOT_RECRUITING
Buffalo
UBMD Peds-Div of Endo/Diabetes
NOT_YET_RECRUITING
Buffalo
Ohio
Centricity Research - Ohio
ACTIVE_NOT_RECRUITING
Columbus
PriMed Clinical Research
ACTIVE_NOT_RECRUITING
Dayton
Pennsylvania
UPMC Child Hosp-Pittsburgh
ACTIVE_NOT_RECRUITING
Pittsburgh
UPMC Child Hosp-Pittsburgh
NOT_YET_RECRUITING
Pittsburgh
South Carolina
Coastal Carolina Research Ctr
ACTIVE_NOT_RECRUITING
North Charleston
Tennessee
Clinical Neuroscience Solutions
WITHDRAWN
Memphis
Texas
Clinical Trials of Texas Inc
ACTIVE_NOT_RECRUITING
San Antonio
Texas Diabetes Institute
ACTIVE_NOT_RECRUITING
San Antonio
Virginia
Health Res of Hampton Roads
ACTIVE_NOT_RECRUITING
Newport News
Virginia Commonwealth Univ
ACTIVE_NOT_RECRUITING
Richmond
Other Locations
Belgium
Cliniques universitaires Saint-Luc
RECRUITING
Brussels
UZ Brussel - Universitair Ziekenhuis Brussel
RECRUITING
Brussels
UZA - Universitair Ziekenhuis Antwerpen
RECRUITING
Edegem
Uz Leuven
RECRUITING
Leuven
Canada
Alberta Children's Hospital
ACTIVE_NOT_RECRUITING
Calgary
Stollery Children's Hospital
ACTIVE_NOT_RECRUITING
Edmonton
Markham Stouffville Hosp
ACTIVE_NOT_RECRUITING
Markham
Maison de Sante Prevention
WITHDRAWN
Montreal
McGill Uni Health Ctre - Glen Site
ACTIVE_NOT_RECRUITING
Montreal
The Hospital for Sick Children
ACTIVE_NOT_RECRUITING
Toronto
BC Children's Hospital
WITHDRAWN
Vancouver
McMaster Children's Hospital
WITHDRAWN
West Hamilton
Denmark
Aalborg Universitetshospital
RECRUITING
Aalborg
Aarhus Universitetshospital, Steno Diabetes Center Aarhus
NOT_YET_RECRUITING
Aarhus
Holbæk Sygehus
RECRUITING
Holbæk
France
Centre Hospitalier Universitaire de Lille-Hopital Jeanne de Flandre
RECRUITING
Lille
Centre Hospitalier Universitaire de Lille-Hopital Jeanne de Flandre
NOT_YET_RECRUITING
Lille
Fondation Lenval Nice
RECRUITING
Nice
Ap-Hp-Hopital Armand Trousseau
RECRUITING
Paris
Centre Hospitalier Universitaire de Rouen-Hopital Charles Nicolle
RECRUITING
Rouen
Centre Hospitalier Universitaire de Rouen-Hopital Charles Nicolle
NOT_YET_RECRUITING
Rouen
Hopital Des Enfants-1
RECRUITING
Toulouse
Germany
Kath. Klinikum Bochum gGmbH - Kinderklinik St. Josef-Hospital
WITHDRAWN
Bochum
Uni-Med. Göttingen - Klinik für Kinder- und Jugendmedizin
RECRUITING
Göttingen
Universitätsmedizin Göttingen - Klinik für Kinder-und Jugendmedizin
NOT_YET_RECRUITING
Göttingen
Auf der Bult - Klinik für Diabetologie, Endokrinologie, Gastroenterologie und Klinische Forschung
NOT_YET_RECRUITING
Hanover
Hannoversche Kinderheilanstalt Auf der Bult - Diabeto-, Endokrino-, Gastroenterologie und Klinische Forschung
RECRUITING
Hanover
Uniklinik Leipzig - Klinik und Poliklinik für Kinder- und Jugendmedizin
RECRUITING
Leipzig
Universitätsklinikum Leipzig - Klinik und Poliklinik für Kinder- und Jugendmedizin
NOT_YET_RECRUITING
Leipzig
Uniklinik Ulm - Dt. Zentrum für Kinder- und Jugendgesundheit (DZKJ)
RECRUITING
Ulm
Universitätsklinikum Ulm für Kinder- und Jugendmedizin
NOT_YET_RECRUITING
Ulm
Greece
U.G.H. Attikon, Pediatric Endocrinology Outpatient Clinic
RECRUITING
Athens
P & A Kyriakou Childrens' Hospital
RECRUITING
Goudi/athens
General University of Patra - Paediatric Department
RECRUITING
Pátrai
'Ippokrateio' General Hospital of Thessaloniki
RECRUITING
Thessaloniki
Ippokrateio Gen Hosp of Thessaloniki, 1st Pediatric Clinic
RECRUITING
Thessaloniki
Italy
IRCCS Meyer Firenze
RECRUITING
Florence
Ospedale dei Bambini Vittore Buzzi
RECRUITING
Milan
Ospedale Pediatrico Bambino Gesu
WITHDRAWN
Roma
IRCCS materno infantile Burlo Garofolo - Clinica Pediatrica
RECRUITING
Trieste
AOU Integrata di Verona - Ospedale Civile Maggiore
RECRUITING
Verona
Mexico
Centro de Estudios de Investigación Metabólicos y Cardio
RECRUITING
Ciudad Madero
Centro de Estudios de Investigación Metabólicos y Cardio
NOT_YET_RECRUITING
Ciudad Madero
CHRISTUS - Latam Hub Excellence and Innovation Center
WITHDRAWN
Monterrey
Consultorio de Endocrinología y Pediatría
NOT_YET_RECRUITING
Puebla City
Poland
Copernicus Podmiot Leczniczy Sp. z o.o.
WITHDRAWN
Gdansk
Górnośląskie Centrum Zdrowia Dziecka Im. Św. Jana Pawla II Samodzielny Publiczny Szpital Kliniczny Nr 6 SUM w Katowicach
RECRUITING
Katowice
UMED Clinical Trials sp. z o.o.
RECRUITING
Lodz
Kliniczny Szpital Wojewodzki nr 2 im. Sw. Jadwigi Krolowej w Rzeszowie
RECRUITING
Rzeszów
ELIPSA - Elżbieta Lipska praktyka lekarska Ośrodek Endokrynologii i Diabetologii Dziecięcej
RECRUITING
Stanisławów Pierwszy Nieporęt
Instytut ''Pomnik - Centrum Zdrowia Dziecka''
NOT_YET_RECRUITING
Warsaw
Instytut ''Pomnik - Centrum Zdrowia Dziecka''
RECRUITING
Warsaw
Klinika Pediatrii, Endokrynologii, Diabetologii I chorób Metabolicznych, Uniwersyteckiego Szpitala Klinicznego in Wrocław
RECRUITING
Wroclaw
Samodzielny Publiczny Szpital Kliniczny Nr 1 im. Prof. Szyszko
RECRUITING
Zabrze
Saudi Arabia
King Abdulaziz Hospital-Al Ahsa-National Guard
RECRUITING
Al Ahsa
National Guard Hospital - Jeddah
RECRUITING
Jeddah
King Faisal Specialist Hospital & Research Centre, Riyadh
RECRUITING
Riyadh
King Khaled University Hospital,King Saud Univ. Med. City
RECRUITING
Riyadh
National Guard Hospital_Riyadh
RECRUITING
Riyadh
Sweden
Barn- och ungdomsmedicinsk mottagning Falun lasarett
NOT_YET_RECRUITING
Falun
Hallands sjukhus Halmstad
RECRUITING
Halmstad
Barnöverviktsenheten, SUS Malmö
WITHDRAWN
Malmo
Sundsvalls sjukhus
RECRUITING
Sundsvall
Akademiska sjukhuset Uppsala
RECRUITING
Uppsala
United Kingdom
Birmingham Children's Hospital
RECRUITING
Birmingham
University Hospitals Bristol & Weston NHS Foundation Trust
RECRUITING
Bristol
Leeds Children's Hospital
RECRUITING
Leeds
Alder Hey Children's Hospital
RECRUITING
Liverpool
Paediatric Services - UCL
RECRUITING
London
Sheffield Children's Hospital
RECRUITING
Sheffield
Southampton General Hospital
RECRUITING
Southampton
Contact Information
Primary
Novo Nordisk
clinicaltrials@novonordisk.com
(+1) 866-867-7178
Time Frame
Start Date: 2024-09-17
Estimated Completion Date: 2031-11-15
Participants
Target number of participants: 500
Treatments
Experimental: Semaglutide
2.4mg or maximum tolerated dose(MTD) injected subcutaneously (under the skin, s.c) once weekly
Related Therapeutic Areas
Sponsors
Leads: Novo Nordisk A/S