Effects of High-intensity Intermittent Exercise With Recovery Hypoxia and Taurine Supplementation in Women With Obesity on Metabolic and Mitochondrial Parameters

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The prevalence of obesity in Brazil is one of the highest in Latin America. As an inflammatory disease, obesity needs to be treated, and one of the best interventions is exercise. This research aims to learn more about the effects of combining high-intensity training, recovery hypoxia, and taurine supplementation. To better understand these effects, the researchers will compare hypoxia and normoxia, as well as taurine and placebo, with all participants training in the same way. The researchers will also investigate mitochondrial respiration and food consumption to connect certain aspects of obesity with overall health.

Eligibility
Participation Requirements
Sex: Female
Minimum Age: 25
Maximum Age: 45
Healthy Volunteers: t
View:

• Women

• Age between 25 - 45 years old;

• BMI between 30 - 35kg/m²;

• Not be on a diet;

• Not be on a physical activity program;

• Not be menopaused.

Locations
Other Locations
Brazil
University of São Paulo, School of Physical Education and Sports of Ribeirão Preto
RECRUITING
Ribeirão Preto
University of São Paulo, School of Physical Education and Sports of Ribeirão Preto.
RECRUITING
Ribeirão Preto
Contact Information
Primary
Ellen C de Freitas
ellenfreitas@usp.br
+55 16 3315-0345
Time Frame
Start Date: 2025-03-01
Estimated Completion Date: 2025-12
Participants
Target number of participants: 50
Treatments
No_intervention: Control
No intervention, only the evaluations will be done.
Placebo_comparator: Normoxia - Placebo
High-intensity interval cycle ergometer train, with inter effort normoxia (FiO2 = 21%).
Placebo_comparator: Normoxia - Taurina
High-intensity interval cycle ergometer train, with inter effort normoxia (FiO2 = 21%).
Placebo_comparator: Hypoxia - Placebo
High-intensity interval cycle ergometer train, with inter effort hypoxia (FiO2 = 12%).
Experimental: Hypoxia - Taurina
High-intensity interval cycle ergometer train, with inter effort hypoxia (FiO2 = 12%).
Related Therapeutic Areas
Sponsors
Collaborators: Fundação de Amparo à Pesquisa do Estado de São Paulo
Leads: University of Sao Paulo

This content was sourced from clinicaltrials.gov