Effect of Daily Fresh Watermelon Consumption on Gut and Cardiometabolic Health in Young Adults With Overweight and Obesity

Status: Recruiting
Location: See location...
Intervention Type: Other
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

The goal of this clinical trial is to evaluate the effect of daily fresh watermelon consumption for 6-weeks on gut health, including microbiome diversity, gut barrier and immune function in young adults with overweight and obesity. The main questions it aims to answer are: 1. Will consuming fresh watermelon daily for 6-weeks will improve intestinal barrier health and increase microbiome diversity such as an increased population of beneficial 'probiotic' bacteria when compared to control participants consuming a low-fat snack? 2. Will consuming fresh watermelon daily for six-weeks will improve other health measures, including body-composition, blood pressure, blood vessel function, blood lipid profiles, and measures of inflammation, as compared to control participants consuming a low-fat snack for the same time period?

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 30
Healthy Volunteers: f
View:

• Between 18 and 30 years old

• Ability to speak and read in English

• Overweight or Obese Class 1 and 2 (BMI ≥ 25 - 39.9 kg/m2)

Locations
United States
Florida
Florida State University - Gut Biome Lab
RECRUITING
Tallahassee
Contact Information
Primary
Ravinder Nagpal, PhD
rnagpal@fsu.edu
850-644-1829
Backup
Cole Patoine, M.S
cjp23a@fsu.edu
Time Frame
Start Date: 2024-10-13
Estimated Completion Date: 2026-08
Participants
Target number of participants: 36
Treatments
Experimental: Watermelon Condition
This group will maintain a normal diet supplemented with 2.5 cups (\~375 grams, 115 kcals, 0.5g fat, 1.5g fiber, 17,225mcg lycopene, 30.75mg vitamin C) of fresh watermelon daily for six weeks
Active_comparator: Control Condition
This group will maintain a normal diet supplemented with an isocaloric control snack (Belvita breakfast sandwich; 115 kcals, 1.5g fiber, 4.5g fat, 0mg lycopene, 0mg vitamin C) as well as 12 ounces of water
Related Therapeutic Areas
Sponsors
Leads: Florida State University

This content was sourced from clinicaltrials.gov