Resting Indicators of Vascular Health and Cardiovascular Reactivity in Females with Normal-Weight Obesity
Most of the time, body weight is evaluated by looking at the ratio of your weight to your height. This measurement is called body mass index or BMI. However, BMI does not account for what your body is actually made up of (e.g., body fat versus muscle), which may be more important for determining cardiovascular disease risk. The investigators aim to understand vascular health in females with a healthy BMI with differing amounts of body fat and muscle mass. We will have participants come to the lab for two different study visits. At one visit, participants will eat a meal high in fat, and at the other visit, participants will undergo a stress task.
• You are 18-50 years old
• Your biological sex is female
• BMI is in normal category (18.5-24.9 kg/m2) - this BMI requirement is due to our research aims
• You are not pregnant or expecting to become pregnant
• You are not postmenopausal
• You have not been diagnosed with a cardiometabolic condition (e.g., cardiovascular disease, type 2 diabetes)
• You have not been diagnosed with a chronic inflammatory condition (e.g., rheumatoid arthritis, inflammatory bowel disease).
• You do not regularly take anti-inflammatory drugs (more than 2x week) or are able to temporarily suspend use of anti-inflammatory drugs.
• You do not use lipid-lowering drugs (e.g., statins), glucose-lowering drugs (e.g., metformin) tobacco products, or any illicit drugs
• You do not have a pacemaker.
• You do not have dietary restrictions prohibiting you from eating the provided meal (e.g., vegan/vegetarian diets, gluten-free diet, relevant food allergies).
• You are able to stay in the supine position in the dark for at least 10 minutes