Investigation of Pharmacokinetic Properties of Single Doses of NNC0662-0419 in Japanese, Chinese and Non-Asian Participants Living With Overweight or Obesity

Status: Recruiting
Location: See location...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 1
SUMMARY

The study is testing the new medicine NNC0662-0419 in people living with overweight or obesity. The purpose of the study is to look into the amount of the new medicine NNC0662-0419 in participants blood after one dose. And also look into how safe and how well the study medicine is tolerated in people living with overweight or obesity. NNC0662-0419 is a new medicine which cannot be prescribed by doctors. NNC0662-0419 is currently being tested in humans and the dose participants will receive has been found safe and tolerable. Participants will get a single dose of NNC0662-0419 given by study staff as a single injection under participants skin. Like all medicines, the study medicine may have side effects. The study will last up to 2 months.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 55
Healthy Volunteers: f
View:

• Male or female (sex at birth) Japanese, Chinese or non-Asian participants (all self-reported).

‣ For Japanese participants: both parents of Japanese descent.

⁃ For Chinese participants: both parents of Chinese descent.

⁃ For non-Asian participants: both parents of non-Asian descent (non-Asian is defined as of countries outside of Asia).

• Age 18-55 years (both inclusive) at the time of signing the informed consent.

• Body mass index (BMI) between 24.0 and 34.9 kilogram per square meter (kg/m\^2) (both inclusive) at screening. Overweight should be due to excess adipose tissue, as judged by the investigator.

• Considered eligible based on the medical history, physical examination, and the results of vital signs, electrocardiogram and clinical laboratory tests performed during the screening visit, as judged by the investigator.

Locations
United States
California
Altasciences Clinical LA, Inc.
RECRUITING
Cypress
Contact Information
Primary
Novo Nordisk
clinicaltrials@novonordisk.com
(+1) 866-867-7178
Time Frame
Start Date: 2025-08-01
Estimated Completion Date: 2025-11-02
Participants
Target number of participants: 99
Treatments
Experimental: NNC0662-0419 (Dose 1)
Participants will receive a single dose (SD) of NNC0662-0419 subcutaneously.
Experimental: NNC0662-0419 (Dose 2)
Participants will receive a SD of NNC0662-0419 subcutaneously.
Experimental: NNC0662-0419 (Dose 3)
Participants will receive a SD of NNC0662-0419 subcutaneously.
Related Therapeutic Areas
Sponsors
Leads: Novo Nordisk A/S

This content was sourced from clinicaltrials.gov

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