Semaglutide Treatment for Alcohol Use Disorder After Metabolic and Bariatric Surgery: A Pilot Randomized Controlled Trial
The purpose of this research study is to evaluate the feasibility of treating Alcohol Use Disorder with Semaglutide after metabolic and bariatric surgery in adults with overweight or obesity.
• Provision of signed and dated informed consent form
• Stated willingness to comply with all study procedures and availability for the duration of the study (up to 6 months: 3-month treatment plus 3-month follow up)
• Age 18 and older
• Have a BMI ≥30 (or BMI ≥27 with a medical comorbidity) and BMI ≤50 kg/m2
• Have had laparoscopic Roux-en-Y gastric bypass or sleeve gastrectomy within the past seven years
• Meet current DSM-5 criteria for Alcohol Use Disorder
• Be an otherwise healthy subject without uncontrolled medical problems, as determined by the study physician and medical co-investigators
• Read, comprehend, and write English at a sufficient level to complete study-related materials
• For females of reproductive potential: use of highly effective contraception and agreement to use such a method during study participation