Long-term Adaptations of Skeletal Muscle in Overweight and Obese Individuals After Hybrid Training
Obesity is a major challenge for public health and renders it imperative to reduce its prevalence. High intensity interval training (HIIT) is a form of exercise training that can efficiently induce weight loss in adults with overweight or obesity, even in the absence of dietary intake manipulation. Hybrid type training represents a form of HIIT, that incorporates both cardiorespiratory and musculoskeletal stimuli, by combining multiple types of exercise into a circuit-type, interval style workout. Recent evidence suggests that long-term participation in hybrid HIIT results in significant health-related benefits. However, the molecular mechanisms driving the chronic effects of hybrid HIIT on cardiometabolic and musculoskeletal health remains to be elucidated.
• BMI: \>25 kg/m2 and \<40 kg/m2
• Untrained individuals (abstain \>1 year from exercise training)
• No dietary intervention over the last 6 months preceding the study
• Low cardiorespiratory fitness level (VO2max: \<45 ml/kg/min)
• No use of any medication, dietary supplements
• Low risk for cardiovascular disease
• A weight loss \<10% over the last 6 months preceding the study
• Free of non-communicable diseases (excluding metabolic syndrome)