Obesity Clinical Trials

Find Obesity Clinical Trials Near You

Novel Respiratory Muscle Training for Improving Cerebrovascular Function and Immune Status in Adults With Obesity

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Millions of adults in America have too much body fat, resulting in obesity. Obesity is detrimental to health and causes disease. Obesity reduces brain health, which causes the brain to function less effectively. Additionally, a lack of exercise contributes to poorer brain health. Most individuals feel they do not have time to exercise. There is a need for a quicker type of training that improves brain health. Newly developed breathing exercises could be a time-efficient, cost-effective, and home-based practice to increase brain health. This practice acts as weightlifting for breathing muscles. These new breathing exercises have already been shown to increase heart health. Heart health is linked to brain health; if an intervention helps the heart, it is likely to also help the brain. It is currently unknown if breathing training can improve brain health in younger adults with obesity. The investigators will utilize the same 8-week program shown to improve heart health. Testing will be conducted before and after the breathing training. The first part of the study will determine if breathing exercises help brain health. Obesity also causes inflammation. This is measured via blood but affects the entire body. It is thought to cause some of the negative outcomes of obesity. By lowering inflammation, it is likely to improve overall health. Breathing exercises may reduce inflammation, but more research is required. The second part of this study will determine whether breathing exercises help reduce inflammation. This study will determine if brain health can be improved in adults with obesity. This could help 40% of American adults with obesity to live longer and healthier lives.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 45
Healthy Volunteers: f
View:

• Body mass index greater than or equal to 30 kg/m2

• Waist circumference greater or equal to 88 cm for females and greater than or equal to 102 cm for males

Locations
United States
Florida
Florida State University
RECRUITING
Tallahassee
Contact Information
Primary
Thomas Bissen, MS
tgb23@fsu.edu
9522121833
Time Frame
Start Date: 2026-01-27
Estimated Completion Date: 2028-05-01
Participants
Target number of participants: 30
Treatments
Active_comparator: High intensity inspiratory muscle strength training
Participants will perform high-resistance inspiratory muscle strength training on a daily basis for eight weeks using a handheld device that produces resistance that increases the effort of breathing in.
Sham_comparator: Low intensity inspiratory muscle strength training
Participants will perform very-low-resistance inspiratory muscle strength training on a daily basis for eight weeks using a handheld device that produces resistance that increases the effort of breathing in.
Related Therapeutic Areas
Sponsors
Leads: Florida State University

This content was sourced from clinicaltrials.gov

Similar Clinical Trials