Obesity Clinical Trials

Find Obesity Clinical Trials Near You

A Placebo-controlled Comparability Study to Compare Two Presentations of Cagrilintide for Weight Management in Participants With Overweight or Obesity

Status: Recruiting
Location: See all (36) locations...
Intervention Type: Drug
Study Type: Interventional
Study Phase: Phase 3
SUMMARY

The purpose of this clinical study is to look at how well a study medicine called cagrilintide helps people living with excess body weight to lose weight. Participants will either get cagrilintide, the active study medicine being tested or placebo, a medicine that has no active medicine in it. Which treatment participants get is decided by chance. Cagrilintide is a new medicine under development that doctors cannot prescribe yet, but it has been tested in humans before. Participants will be in this clinical study for about 9 months.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Healthy Volunteers: f
View:

• Informed consent obtained before any study-related activities. Study-related activities are any procedures that are carried out as part of the study, including activities to determine suitability for the study.

• Male or female (sex assigned at birth, inclusive of all gender identities).

• Age 18 years or above at the time of signing the informed consent.

• Body mass index (BMI) greater than or equal to (\>=) 30.0 kilograms per square meter (kg/m\^2), or BMI \>= 27.0 kg/m\^2 with the presence of at least one weight related comorbidity including, but not limited to, hypertension, dyslipidaemia, obstructive sleep apnoea or cardiovascular disease.

Locations
United States
Georgia
Hope Clin Res & Wellness
RECRUITING
Conyers
Hawaii
East West Med Res Inst
RECRUITING
Honolulu
Illinois
Walgreens - Store 11760
NOT_YET_RECRUITING
Oak Park
Indiana
Midwest Inst For Clin Res
RECRUITING
Indianapolis
Kentucky
The Alliance for Multispecialty Research LLC AMR
RECRUITING
Lexington
North Carolina
PharmQuest
RECRUITING
Greensboro
KDCILM, LLC & Accellacare US, Inc.
RECRUITING
Wilmington
South Carolina
Coastal Carolina Res Ctr
RECRUITING
North Charleston
Virginia
Health Res of Hampton Roads
RECRUITING
Newport News
National Clin Res Inc.
RECRUITING
Richmond
Selma Medical Associates
RECRUITING
Winchester
Other Locations
Greece
General Hospital Of Athens Alexandra - Department of Endocrinology, Diabetes Center
RECRUITING
Athens
General Hospital Of Athens G Gennimatas - Department of Endocrinology
RECRUITING
Athens
General Hospital Venizeleio-Pananeio - Diabetic Clinic
RECRUITING
Irakleio
Athens Medical Center S.A. (Iatriko Peristeriou) - Diabetes, obesity and cardiometabolic diseases department
RECRUITING
Peristeri
Ippokratio General Hospital Of Thessaloniki - B' Internal Medicine clinic
RECRUITING
Thessaloniki
St. Luke's Hospital S.A. - Endocrinology Department and Obesity Clinic
RECRUITING
Thessaloniki
Hungary
Stúdium Egészségház Kft.
RECRUITING
Kalocsa
Trial Pharma Kft.
RECRUITING
Kecskemét
Borbánya Praxis E.Ü. Kft.
RECRUITING
Nyíregyháza
KomplexLabor Diagnosztika Kft.
RECRUITING
Szeged
Portugal
ULS Do Oeste E.P.E. - Unidade Caldas da Rainha_CAMI - Unidade de Diabetes
RECRUITING
Caldas Da Rainha
ULS Do Baixo Mondego, E.P.E. - HDFF_Serviço Cirurgia (Esp. Endocrinologia)
RECRUITING
Figueira Da Foz Municipality
Hospital São Francisco, S.A_EECC
RECRUITING
Leiria
APDP - Associação Protectora dos Diabéticos de Portugal
RECRUITING
Lisbon
CVP Hospital Cruz Vermelha_Cardiologia
RECRUITING
Lisbon
ULS De Gaia/Espinho_H.Santos Silva_Endocrinologia
RECRUITING
Vila Nova De Gaia
Serbia
Endocrinology, Diabetes and Metabolism Diseases Clinic
RECRUITING
Belgrade
Institute for Cardiovascular Diseases of Vojvodina - Sremska Kamenica
RECRUITING
Kamenitz
Clinical Centre Nis, Endocrinology, Diabetes and Metabolism
RECRUITING
Niš
University Clinical Centre Nis, Clinic for Cardiology
RECRUITING
Niš
Clin. Centre Vojvodina, Clin. endocr., diab. and met. dis.
RECRUITING
Novi Sad
Sweden
Skånes Universitets Sjukhus
RECRUITING
Lund
Forsåker vårdcentral
RECRUITING
Mölndal
Örebro US - Överviktsenheten
RECRUITING
Örebro
Dalecarlia Clinical Research AB
RECRUITING
Rättvik
Contact Information
Primary
Novo Nordisk
clinicaltrials@novonordisk.com
(+1) 866-867-7178
Time Frame
Start Date: 2026-08-04
Estimated Completion Date: 2027-07-06
Participants
Target number of participants: 285
Treatments
Experimental: Cagrilintide + placebo semaglutide in device 1 and placebo cagrilintide in device 2
Participants will receive cagrilintide along with placebo matched to semaglutide in device 1 and placebo matched to cagrilintide in device 2 subcutaneously (s.c) once weekly for 26 weeks.
Experimental: Cagrilintide in device 2 and placebo cagrilintide + placebo semaglutide in device 1
Participants will receive cagrilintide in device 2 and placebo matched to cagrilintide along with placebo matched to semaglutide in device 1 s.c once weekly for 26 weeks.
Placebo_comparator: Placebo cagrilintide in device 2 and placebo cagrilintide + placebo semaglutide in device 1
Participants will receive placebo matched to cagrilintide in device 2 and placebo matched to cagrilintide along with placebo matched to semaglutide in device 1 s.c once weekly for 26 weeks.
Related Therapeutic Areas
Sponsors
Leads: Novo Nordisk A/S

This content was sourced from clinicaltrials.gov

Similar Clinical Trials