Obesity Clinical Trials

• Participant must be ≥18 years of age inclusive, or the legal age of consent in the jurisdiction in which the study is taking place at screening.

• Have a BMI ≥ 30 kg/m2 or a BMI ≥ 27 kg/m2 and presence of at least 1 of the following weight-related comorbidities (treated or untreated) at screening:

‣ Hypertension

⁃ Dyslipidemia

⁃ Obstructive sleep apnea

⁃ Cardiovascular disease (for example, ischemic cardiovascular disease, New York Heart Association Functional Class I-III heart failure).

• Have a history of at least 1 self-reported unsuccessful dietary effort to lose body weight.