Eating-related Self-regulation and Its Neural Substrates as Mechanisms Underlying the Sleep/Eating Behavior Association in Children With Overweight/Obesity: An Ecological Momentary Assessment Study

Status: Recruiting
Location: See all (2) locations...
Intervention Type: Behavioral
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Overweight/obesity and inadequate sleep are prevalent, and frequently co-occurring, health risks among children, both of which are associated with serious medical and psychosocial health complications including risk for cardiovascular disease. Although the investigator's data suggest that disrupted or shortened sleep may be causally associated with increased energy intake and weight gain in children, and with self-regulation and neural response to food cues in adults, understanding of mechanisms involved in the sleep/eating association is incomplete, thereby impeding development of targeted, optimally timed intervention strategies. The proposed mechanistic clinical trial aims to assess the effects of an experimental sleep manipulation on eating-related self-regulation and its neural substrates, and on real-world eating behavior, among children with overweight/obesity, which will help guide research efforts towards the refinement of prevention and intervention strategies targeting sleep and its eating-related correlates to curb weight gain throughout development.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 8
Maximum Age: 12
Healthy Volunteers: t
View:

• at risk for obesity (BMI\>=85th percentile for age and sex OR BMI\>=50th percentile for age and sex with at least one obese parent)

• average time in bed between 9.5-10.5 hours/night

Locations
United States
Pennsylvania
University of Pittsburgh
RECRUITING
Pittsburgh
Rhode Island
Weight Control & Diabetes Research Center
COMPLETED
Providence
Contact Information
Primary
Erin Stalvey, B.S.
stalveyer@upmc.edu
412-586-9066
Backup
Victoria Bell, B.A.
bitelab@upmc.edu
412-586-9081
Time Frame
Start Date: 2019-08-15
Estimated Completion Date: 2026-05-29
Participants
Target number of participants: 120
Treatments
Experimental: Sleep restriction followed by extension
Children will spend 8 hours in bed for one week, engage in one week of wash-out, and then spend 11 hours in bed for one week.
Experimental: Sleep extension followed by restriction
Children will spend 11 hours in bed for one week, engage in one week of wash-out, and then spend 8 hours in bed for one week.
Authors
Andrea B. Goldschmidt
Related Therapeutic Areas
Sponsors
Leads: University of Pittsburgh
Collaborators: National Heart, Lung, and Blood Institute (NHLBI)

This content was sourced from clinicaltrials.gov