Brain Circuitry of Inhibitory Control: Effects of Modulation

Status: Recruiting
Location: See location...
Intervention Type: Device
Study Type: Interventional
Study Phase: Not Applicable
SUMMARY

Inhibitory control is relevant to many clinical disorders, including substance abuse/dependence, obsessive-compulsive disorder, and attention-deficit hyperactivity disorder. This proposal is designed to assess brain networks related to response inhibition in healthy young adults, and use neuromodulation to change these networks and behavioral performance on a response inhibition task. Having an understanding of the brain mechanisms involved in response inhibition may enable us to improve pre-existing treatments for disorders with inhibitory control difficulties.

Eligibility
Participation Requirements
Sex: All
Minimum Age: 18
Maximum Age: 25
Healthy Volunteers: t
View:

• Low (\<1sd below the mean on the BRIEF-Inhibit) or high (\>1sd above the mean on BRIEF-Inhibit scale)

• English fluency to ensure comprehension of study measures and instructions.

Locations
United States
Rhode Island
Butler Hospital
RECRUITING
Providence
Contact Information
Primary
Nicole McLaughlin, PhD
nmclaughlin@butler.org
4014556608
Time Frame
Start Date: 2019-11-14
Estimated Completion Date: 2024-04-01
Participants
Target number of participants: 108
Treatments
No_intervention: Cautious Participants
Participants who have low scores on a self-report of inhibitory control abilities (BRIEF-Inhibit).
Experimental: Impulsive Participants- Active Stimulation
Participants who have high scores on a self-report of inhibitory control abilities (BRIEF-Inhibit) who are randomized to active stimulation.
Sham_comparator: Impulsive Participants- Sham Stimulation
Participants who have high scores on a self-report of inhibitory control abilities (BRIEF-Inhibit) who are randomized to sham stimulation.
Related Therapeutic Areas
Sponsors
Leads: Butler Hospital

This content was sourced from clinicaltrials.gov